Interfacial Cholesterol Binding Sites on TRPs
Transient Receptor Potential Channels [TRPP - TRPV6]
[Chl gives the letter assigned to cholesterol molecules in the PDB files; Units of E, kcals/mol with molar concentration units]
| PDB | Chl | E | Local Residues |
| TRPP | |||
| TRPP (PC2), closed, Human 5k47 | |||
| 5k47_EC | E | -14.2 | Leu228.A, Ile232.A, Cys235.A, Tyr239.A, Ser244.A, Trp570.A, Gln613.B, Tyr616.B, Phe629.B |
| F | -14.1 | Leu228.B, Ile232.B, Cys235.B, Tyr239.B, Trp570.B, Gln613.C, Tyr616.C, Phe629.C | |
| G | -13.5 | Val513.C, Leu517.C, Ile556.C, Gln557.C, Asn560.C, Ile561.C, Val564.C, Val655.D | |
| H | -13.5 | Val513.B, Leu517.B, Gln557.B, Asn560.B, Ile561.B, Val564.B, Phe568.B, Val655.C, Leu656.C | |
| I | -12.5 | Cys509.A, Val513.A, Leu517.A, Gln557.A, Asn560.A, Ile561.A, Val564.A, Phe568.A, Val655.B, Leu656.B | |
| J | -12.8 | Val512.B, Val513.B, Val516.B, Leu517.B, Val520.B, Tyr553.B, Gln557.B, Ile561.B | |
| K | -12.8 | Ile492.C, Val516.C, Val519.C, Val520.C, Gly523.C, Ile524.C, Tyr527.C, Arg528.C | |
| L | -12.5 | Ile492.B, Val516.B, Val519.B, Val520.B, Gly523.B, Ile524.B, Tyr527.B, Arg528.B | |
| M | -14.1 | Gln613.A, Tyr616.A, Phe629.A, Leu228.D, Ile232.D, Cys235.D, Tyr239.D, Trp570.D | |
| N | -14.0 | Leu228.C, Ile232.C, Cys235.C, Tyr239.C, Trp570.C, Gln613.D, Tyr616.D, Phe629.D | |
| O | -13.5 | Val655.A, Leu656.A, Val513.D, Leu517.D, Gln557.D, Asn560.D, Ile561.D, Val564.D, Phe568.D | |
| P | -12.6 | Ile492.A, Val516.A, Val519.A, Val520.A, Gly523.A, Ile524.A, Tyr527.A, Arg528.A | |
| Q | -12.5 | Ile492.D, Val516.D, Val519.D, Val520.D, Gly523.D, Ile524.D, Tyr527.D, Arg528.D | |
| R | -13.1 | Val512.D, Val513.D, Val516.D, Leu517.D, Val520.D, Tyr553.D, Gln557.D, Ile561.D | |
| S | -13.0 | Val512.A, Val513.A, Val516.A, Leu517.A, Val520.A, Tyr553.A, Trp554.A, Ile561.A | |
| 5k47_IC | E | -14.0 | Phe503.C, Arg504.C, Phe506.C, Cys509.C, Phe567.C, Phe568.C, Tyr611.D, Thr663.D |
| F | -13.9 | Leu228.B, Trp570.B, Leu573.B, Phe576.B, Ile577.B, Asn578.B, Phe579.B, Ile602.C, Ile606.C, Leu609.C | |
| G | -13.9 | Phe503.B, Arg504.B, Phe506.B, Cys509.B, Phe567.B, Phe568.B, Tyr611.C, Thr663.C | |
| H | -13.9 | Leu228.A, Trp570.A, Leu573.A, Phe576.A, Ile577.A, Asn578.A, Phe579.A, Ile602.B, Ile606.B, Leu609.B | |
| I | -13.1 | Ile495.B, His498.B, Lys499.B, Leu500.B, Tyr502.B, Phe503.B, Val512.B, Val516.B, Val519.B | |
| J | -13.1 | Ile495.C, Lys499.C, Leu500.C, Tyr502.C, Phe503.C, Val512.C, Val516.C, Val519.C | |
| K | -13.2 | Ile495.A, Lys499.A, Leu500.A, Tyr502.A, Phe503.A, Val512.A, Val516.A, Val519.A | |
| L | -13.2 | Arg504.A, Phe506.A, Cys509.A, Val564.A, Phe568.A, Ile659.B, Thr663.B, Phe667.B | |
| M | -13.9 | Tyr611.A, Thr663.A, Phe503.D, Arg504.D, Phe506.D, Cys509.D, Phe567.D, Phe568.D | |
| N | -13.9 | Leu228.C, Trp570.C, Leu573.C, Phe576.C, Ile577.C, Asn578.C, Phe579.C, Asn580.C, Ile602.D, Ile606.D, Leu609.D | |
| O | -13.9 | Ile602.A, Ile606.A, Leu609.A, Leu228.D, Trp570.D, Leu573.D, Phe576.D, Ile577.D, Phe579.D | |
| P | -13.1 | Ile495.D, Lys499.D, Leu500.D, Tyr502.D, Phe503.D, Val512.D, Val516.D, Val519.D | |
| TRPP (PC2), closed, with Ca, PA and palmitic acid, Human 5mke | |||
| 5mke_EC | E | -18.3 | Cys235.C, Thr238.C, Tyr239.C, Met242.C, Ser243.C, Ser244.C, Trp570.C, Leu609.D, Tyr616.D, Phe629.D |
| F | -18.0 | Cys235.B, Thr238.B, Tyr239.B, Met242.B, Ser243.B, Ser244.B, Trp570.B, Leu609.C, Tyr616.C, Phe629.C | |
| G | -15.3 | Arg654.A, Val655.A, Pro658.A, Ile659.A, Thr662.A, Trp380.D, Phe605.D, Gln630.D, Ile633.D, Phe634.D | |
| H | -15.0 | Trp380.A, Phe605.A, Gln630.A, Ile633.A, Phe634.A, Arg654.B, Val655.B, Pro658.B, Ile659.B, Thr662.B | |
| I | -16.2 | Cys235.A, Thr238.A, Tyr239.A, Met242.A, Ser243.A, Trp570.A, Leu609.B, Gln613.B, Tyr616.B, Phe629.B | |
| J | -15.9 | Gln613.A, Tyr616.A, Phe629.A, Cys235.D, Thr238.D, Tyr239.D, Met242.D, Ser243.D, Ser244.D, Trp570.D | |
| K | -15.0 | Trp380.B, Phe605.B, Gln630.B, Ile633.B, Phe634.B, Arg654.C, Val655.C, Pro658.C, Ile659.C, Thr662.C | |
| 5mke_IC | E | -14.2 | Leu641.A, Gly642.A, Asp643.A, Phe669.A, Leu673.A, Leu677.A, Leu641.B, Gly642.B, Asp643.B, Phe669.B, Leu673.B, Leu677.B, Ile640.C, Leu641.C, Gly642.C, Asp643.C, Phe669.C, Leu673.C, Leu677.C, Leu641.D, Gly642.D, Asp643.D, Leu677.D |
| F | -13.7 | Tyr611.A, Leu614.A, Val618.A, Leu656.A, Gly657.A, Ile659.A, Tyr660.A, Thr663.A, Phe667.A, Val564.D, Phe567.D, Phe568.D, Ser591.D | |
| G | -13.5 | Leu510.B, Val564.B, Phe567.B, Phe568.B, Ser591.B, Tyr611.C, Val655.C, Leu656.C, Gly657.C, Ile659.C, Tyr660.C, Thr663.C, Phe667.C | |
| H | -13.5 | Leu228.B, Leu231.B, Ile232.B, Tyr239.B, Trp570.B, Leu573.B, Phe576.B, Ile577.B, Ile606.C | |
| I | -13.5 | Ile606.A, Leu228.D, Leu231.D, Ile232.D, Trp570.D, Leu573.D, Phe576.D, Ile577.D | |
| J | -13.6 | Leu228.C, Leu231.C, Trp570.C, Leu573.C, Phe576.C, Ile577.C, Ile606.D, Phe629.D | |
| K | -14.4 | Val564.A, Phe567.A, Phe568.A, Ser591.A, Tyr611.B, Leu614.B, Val618.B, Leu656.B, Gly657.B, Ile659.B, Tyr660.B, Thr663.B, Phe667.B | |
| L | -13.0 | Phe598.C, Gln630.C, Ile633.C, Phe634.C, Ile659.D, Thr662.D, Phe666.D, Phe667.D | |
| M | -13.4 | Leu228.A, Leu231.A, Trp570.A, Leu573.A, Phe576.A, Ile577.A, Asn578.A, Ile606.B | |
| TRPP (PC2), closed, with Ca, PA and palmitic acid, Human 5mkf | |||
| 5mkf_EC | E | -15.5 | Trp380.A, Gln630.A, Phe634.A, Arg654.B, Val655.B, Pro658.B, Ile659.B, Thr662.B, Thr663.B, Phe667.B |
| F | -15.3 | Arg654.A, Val655.A, Pro658.A, Ile659.A, Thr662.A, Trp380.D, Gln630.D, Ile633.D, Phe634.D | |
| G | -15.3 | Phe605.A, Leu609.A, Gln613.A, Tyr616.A, Phe629.A, Thr238.D, Tyr239.D, Met242.D, Ser244.D | |
| H | -15.2 | Thr238.C, Tyr239.C, Ser244.C, Phe605.D, Leu609.D, Gln613.D, Tyr616.D, Phe629.D | |
| I | -14.0 | Leu510.A, Val513.A, Leu517.A, Gln557.A, Asn560.A, Ile561.A, Val564.A, Phe568.A, Val655.B, Leu656.B | |
| J | -13.9 | Val655.A, Leu656.A, Leu510.D, Val513.D, Leu517.D, Tyr553.D, Gln557.D, Asn560.D, Ile561.D, Val564.D, Phe568.D | |
| K | -14.0 | Val512.A, Val513.A, Val516.A, Leu517.A, Val520.A, Tyr553.A, Trp554.A, Gln557.A, Ile561.A | |
| L | -13.9 | Val512.D, Val513.D, Val516.D, Leu517.D, Val520.D, Tyr553.D, Trp554.D, Gln557.D, Ile561.D | |
| M | -15.4 | Trp380.C, Gln630.C, Ile633.C, Phe634.C, Arg654.D, Val655.D, Pro658.D, Ile659.D, Thr662.D | |
| N | -15.3 | Thr238.A, Tyr239.A, Ser244.A, Phe605.B, Leu609.B, Gln613.B, Tyr616.B, Phe629.B | |
| O | -15.3 | Trp380.B, Gln630.B, Ile633.B, Phe634.B, Arg654.C, Val655.C, Pro658.C, Ile659.C, Thr662.C, Thr663.C, Phe666.C | |
| P | -15.2 | Thr238.B, Tyr239.B, Met242.B, Ser244.B, Phe605.C, Leu609.C, Gln613.C, Tyr616.C, Phe629.C | |
| Q | -14.1 | Leu510.C, Val513.C, Leu517.C, Gln557.C, Asn560.C, Ile561.C, Val564.C, Phe568.C, Val655.D, Leu656.D | |
| R | -14.0 | Leu510.B, Val513.B, Leu517.B, Gln557.B, Asn560.B, Ile561.B, Val564.B, Phe568.B, Val655.C, Leu656.C | |
| S | -13.9 | Val512.B, Val513.B, Val516.B, Leu517.B, Val520.B, Tyr553.B, Trp554.B, Gln557.B, Ile561.B | |
| T | -13.9 | Val512.C, Val513.C, Val516.C, Leu517.C, Val520.C, Tyr553.C, Trp554.C, Gln557.C, Ile561.C | |
| 5mkf_IC | E | -14.2 | Ile602.A, Ile606.A, Gln613.A, Leu231.D, Cys235.D, Trp570.D, Leu573.D, Ile577.D, Asn578.D, Phe579.D, Asn580.D |
| F | -14.2 | Leu231.C, Cys235.C, Trp570.C, Leu573.C, Ile577.C, Asn578.C, Asn580.C, Ile602.D, Ile606.D, Gln613.D | |
| G | -13.7 | Tyr611.A, Leu614.A, Leu656.A, Ile659.A, Tyr660.A, Phe667.A, Phe506.D, Leu510.D, Val564.D, Phe567.D, Phe568.D, Phe598.D | |
| H | -13.7 | Phe506.C, Leu510.C, Val564.C, Phe567.C, Phe568.C, Phe598.C, Tyr611.D, Leu614.D, Leu656.D, Ile659.D, Phe667.D | |
| I | -13.7 | Phe506.A, Leu510.A, Val564.A, Phe567.A, Phe568.A, Phe598.A, Tyr611.B, Leu614.B, Leu656.B, Ile659.B, Phe667.B | |
| J | -13.1 | Thr662.A, Phe598.D, Gly599.D, Ala601.D, Ile602.D, Phe605.D, Ile633.D, Phe634.D | |
| K | -13.0 | Phe598.A, Gly599.A, Ala601.A, Ile602.A, Phe605.A, Ile633.A, Phe634.A, Thr662.B, Arg581.D | |
| L | -14.4 | Leu231.B, Cys235.B, Trp570.B, Leu573.B, Ile577.B, Asn578.B, Phe579.B, Asn580.B, Ile602.C, Ile606.C, Gln613.C | |
| M | -14.3 | Leu231.A, Cys235.A, Trp570.A, Leu573.A, Ile577.A, Asn578.A, Phe579.A, Asn580.A, Ile602.B, Ile606.B, Gln613.B | |
| N | -13.7 | Phe506.B, Leu510.B, Val564.B, Phe567.B, Phe568.B, Phe598.B, Leu614.C, Leu656.C, Ile659.C, Tyr660.C, Phe667.C | |
| O | -13.1 | Arg581.B, Phe598.C, Gly599.C, Ala601.C, Ile602.C, Phe605.C, Ile633.C, Phe634.C, Thr662.D | |
| P | -13.2 | Asn580.A, Phe598.B, Gly599.B, Ala601.B, Ile602.B, Phe605.B, Phe634.B, Thr662.C | |
| TRPP (PKD2), closed, Human 5t4d | |||
| 5t4d_EC | E | -16.4 | Val655.C, Leu656.C, Ile659.C, Cys509.D, Val513.D, Leu517.D, Gln557.D, Asn560.D, Ile561.D, Val564.D, Phe568.D |
| F | -16.4 | Val655.B, Leu656.B, Ile659.B, Cys509.C, Val513.C, Leu517.C, Ile556.C, Gln557.C, Asn560.C, Ile561.C, Val564.C, Phe568.C | |
| G | -15.0 | Arg654.B, Val655.B, Pro658.B, Ile659.B, Thr662.B, Trp380.C, Ile602.C, Phe605.C, Gln630.C, Ile633.C, Phe634.C | |
| H | -15.0 | Arg654.C, Val655.C, Pro658.C, Ile659.C, Thr662.C, Trp380.D, Ile602.D, Phe605.D, Gln630.D, Ile633.D, Phe634.D | |
| I | -13.4 | Val512.C, Val513.C, Val516.C, Leu517.C, Val520.C, Tyr553.C, Gln557.C, Ile561.C | |
| J | -13.3 | Val512.D, Val513.D, Val516.D, Leu517.D, Val520.D, Tyr553.D, Gln557.D, Ile561.D | |
| K | -16.4 | Val655.A, Leu656.A, Ile659.A, Cys509.B, Val513.B, Leu517.B, Gln557.B, Asn560.B, Ile561.B, Val564.B, Phe568.B | |
| L | -16.4 | Cys509.A, Val513.A, Leu517.A, Gln557.A, Asn560.A, Ile561.A, Val564.A, Phe568.A, Val655.D, Leu656.D, Ile659.D | |
| M | -15.0 | Trp380.A, Ile602.A, Phe605.A, Gln630.A, Ile633.A, Phe634.A, Arg654.D, Val655.D, Pro658.D, Ile659.D, Thr662.D | |
| N | -15.0 | Arg654.A, Val655.A, Pro658.A, Ile659.A, Thr662.A, Trp380.B, Ile602.B, Phe605.B, Gln630.B, Ile633.B, Phe634.B | |
| O | -13.3 | Val512.A, Val513.A, Val516.A, Leu517.A, Val520.A, Tyr553.A, Gln557.A, Ile561.A | |
| P | -13.3 | Val512.B, Val513.B, Val516.B, Leu517.B, Val520.B, Tyr553.B, Gln557.B, Ile561.B | |
| 5t4d_IC | E | -16.6 | Phe506.A, Trp507.A, Phe567.A, Phe568.A, Ile571.A, Ser587.A, Thr588.A, Met590.A, Ser591.A, Ile607.D, Tyr611.D, Thr663.D, Phe667.D |
| F | -16.6 | Ile607.B, Tyr611.B, Thr663.B, Phe667.B, Phe506.C, Trp507.C, Phe567.C, Phe568.C, Ile571.C, Ser587.C, Met590.C, Ser591.C | |
| G | -16.6 | Ile607.C, Tyr611.C, Thr663.C, Phe667.C, Phe506.D, Trp507.D, Phe567.D, Phe568.D, Ile571.D, Ser587.D, Thr588.D, Met590.D, Ser591.D | |
| H | -13.0 | Thr662.B, Thr663.B, Phe666.B, Phe667.B, Arg504.C, Phe506.C, Ala594.C, Phe598.C, Phe605.C | |
| I | -13.0 | Thr662.C, Thr663.C, Phe666.C, Phe667.C, Phe506.D, Ala594.D, Phe598.D, Phe605.D | |
| J | -12.5 | Leu609.C, Leu221.D, Leu224.D, Leu228.D, Trp570.D, Leu573.D, Phe576.D, Phe579.D | |
| K | -12.5 | Leu221.A, Leu224.A, Leu228.A, Trp570.A, Leu573.A, Phe576.A, Phe579.A, Ile606.D, Leu609.D | |
| L | -12.5 | Leu609.B, Leu221.C, Leu224.C, Leu228.C, Trp570.C, Leu573.C, Phe576.C, Phe579.C | |
| M | -16.6 | Ile607.A, Tyr611.A, Thr663.A, Phe667.A, Phe506.B, Trp507.B, Phe567.B, Phe568.B, Ile571.B, Ser587.B, Met590.B, Ser591.B | |
| N | -13.0 | Thr662.A, Thr663.A, Phe666.A, Phe667.A, Arg504.B, Phe506.B, Ala594.B, Phe598.B, Phe605.B | |
| O | -12.9 | Phe506.A, Ala594.A, Phe598.A, Phe605.A, Thr662.D, Thr663.D, Phe666.D, Phe667.D | |
| P | -12.5 | Leu609.A, Leu221.B, Leu224.B, Leu228.B, Trp570.B, Leu573.B, Phe576.B, Phe579.B | |
| TRPP (3PKD2/1PKD1), closed, Human 6a70 | |||
| 6a70_EC | C | -13.7 | Leu4031.B, His4081.B, Leu4085.B, Arg654.G, Val655.G, Pro658.G, Ile659.G, Thr662.G |
| D | -13.7 | Phe634.A, Phe637.A, Ile640.A, Leu641.A, Leu673.A, Phe676.A, Leu677.A, Leu4095.B, Gly4097.B | |
| E | -13.3 | Leu228.A, Ile232.A, Cys235.A, Tyr239.A, Trp570.A, Leu573.A, Ile577.A, Val4038.B, Gln4042.B, Ile4045.B, Pro4084.B | |
| H | -13.3 | Phe485.A, Val488.A, Val489.A, Ile492.A, Leu493.A, Ile522.A, Gly523.A, Asn525.A, Ile526.A | |
| I | -12.9 | Leu3318.B, Leu3590.B, Leu3597.B, Gly3896.B, Leu3897.B, Leu3901.B, Leu3902.B, Val3905.B, Cys3906.B, Leu3909.B | |
| J | -12.9 | Glu491.F, Val516.F, Val519.F, Val520.F, Gly523.F, Ile524.F, Tyr527.F, Arg528.F | |
| K | -14.4 | Arg654.A, Val655.A, Pro658.A, Ile659.A, Thr662.A, Thr663.A, Phe666.A, Phe598.F, Phe605.F, Gln630.F, Phe634.F | |
| L | -14.1 | Leu656.A, Phe506.F, Cys509.F, Val513.F, Leu517.F, Gln557.F, Asn560.F, Ile561.F, Val564.F, Phe568.F | |
| M | -13.9 | Arg654.F, Val655.F, Pro658.F, Ile659.F, Thr662.F, Thr663.F, Phe666.F, Phe598.G, Ala601.G, Phe605.G, Gln630.G, Phe634.G | |
| N | -13.5 | Ile602.F, Ile606.F, Leu609.F, Phe629.F, Gln630.F, Ile633.F, Trp570.G, Leu573.G | |
| O | -13.6 | Val655.F, Leu656.F, Ile659.F, Phe506.G, Val513.G, Leu517.G, Gln557.G, Asn560.G, Ile561.G, Val564.G, Phe568.G | |
| 6a70_IC | C | -16.0 | Ile495.A, His498.A, His501.A, Tyr502.A, Phe503.A, Arg504.A, Val513.A, Val516.A |
| D | -15.7 | Trp3263.B, Leu3264.B, Ser3265.B, Ile3266.B, Cys3284.B, Ile3288.B, Leu3589.B, Phe3596.B, Phe3600.B, Leu3675.B, Leu3679.B | |
| E | -14.1 | Trp570.A, Ile577.A, Phe579.A, Asn580.A, Met583.A, Leu4031.B, Val4034.B, Val4035.B, Val4038.B | |
| H | -13.6 | Met3089.B, Leu3999.B, Ala4002.B, Gln4005.B, Leu4006.B, Phe4008.B, Val4009.B, Ile606.G, Gln613.G | |
| I | -13.3 | Arg222.A, Glu223.A, Thr226.A, Phe230.A, Phe482.A, Phe483.A, Tyr486.A, Glu490.A | |
| J | -16.3 | Ile659.F, Thr663.F, Phe667.F, Phe506.G, Trp507.G, Phe567.G, Phe568.G, Ile571.G, Phe574.G, Ser587.G, Met590.G, Ser591.G | |
| K | -13.7 | Phe506.G, Val513.G, Leu517.G, Val564.G, Phe568.G, Ala594.G, Lys595.G, Phe598.G | |
| L | -13.6 | Glu491.G, Ile495.G, His501.G, Phe503.G, Arg504.G, Val512.G, Val516.G, Val519.G | |
| M | -13.6 | Thr662.F, Thr663.F, Phe666.F, Phe667.F, Ala594.G, Phe598.G, Phe605.G, Phe637.G | |
| N | -13.6 | Thr662.A, Thr663.A, Phe666.A, Phe667.A, Phe506.F, Ala594.F, Phe598.F, Phe605.F | |
| O | -14.7 | Phe598.F, Ile602.F, Ile606.F, Leu609.F, Phe629.F, Trp570.G, Leu573.G, Ile577.G, Phe579.G, Asn580.G | |
| P | -14.5 | Ile659.A, Thr663.A, Phe667.A, Phe506.F, Phe568.F, Ile571.F, Phe574.F, Ser587.F, Met590.F, Ser591.F, Ala594.F | |
| Q | -14.2 | Ile602.A, Ile606.A, Leu609.A, Trp570.F, Leu573.F, Ile577.F, Phe579.F, Asn580.F | |
| TRPP (PKD2L1), closed, Human 6d1w | |||
| 6d1w_EC | E | -14.2 | Arg654.A, Val655.A, Pro658.A, Ile659.A, Thr662.A, Trp380.D, Phe605.D, Gln630.D, Ile633.D, Phe634.D |
| F | -14.2 | Trp380.B, Phe605.B, Gln630.B, Ile633.B, Phe634.B, Arg654.D, Val655.D, Pro658.D, Ile659.D, Thr662.D | |
| G | -14.3 | Arg654.B, Val655.B, Pro658.B, Ile659.B, Thr662.B, Trp380.C, Phe605.C, Gln630.C, Ile633.C, Phe634.C | |
| H | -14.2 | Trp380.A, Phe605.A, Gln630.A, Ile633.A, Phe634.A, Arg654.C, Val655.C, Pro658.C, Ile659.C, Thr662.C | |
| 6d1w_IC | E | -14.6 | Ile659.B, Thr662.B, Thr663.B, Phe666.B, Phe667.B, Ala594.C, Lys595.C, Phe598.C, Phe605.C, Ile633.C, Phe634.C |
| F | -14.6 | Ile659.A, Thr662.A, Thr663.A, Phe666.A, Phe667.A, Ala594.D, Lys595.D, Leu597.D, Phe598.D, Phe605.D, Ile633.D, Phe634.D | |
| G | -14.3 | Val488.D, Glu491.D, Ile492.D, Leu493.D, Val512.D, Val516.D, Val519.D, Val520.D | |
| H | -14.0 | Val564.B, Phe568.B, Ala594.B, Lys595.B, Leu597.B, Phe598.B, Ile659.D, Thr663.D, Phe667.D, Phe670.D | |
| I | -14.0 | Val488.B, Glu491.B, Ile492.B, Leu493.B, Val512.B, Val516.B, Val519.B, Val520.B | |
| J | -14.3 | Val488.C, Glu491.C, Ile492.C, Leu493.C, Val512.C, Val516.C, Val519.C, Val520.C | |
| K | -14.2 | Val488.A, Glu491.A, Ile492.A, Leu493.A, Val512.A, Val516.A, Val519.A, Val520.A | |
| L | -14.0 | Val564.A, Phe568.A, Ala594.A, Lys595.A, Leu597.A, Phe598.A, Ile659.C, Thr663.C, Phe667.C, Phe670.C | |
| TRPP (PKD2L1), closed, Human 6du8 | |||
| 6du8_EC | E | -16.6 | Ile108.C, Leu111.C, Val112.C, Tyr119.C, Thr122.C, Ser124.C, Trp450.C, Tyr496.D, Phe509.D |
| F | -16.6 | Ile108.A, Leu111.A, Val112.A, Tyr119.A, Thr122.A, Ser124.A, Trp450.A, Tyr496.C, Phe509.C | |
| G | -13.6 | Ile388.C, Leu391.C, Val392.C, Leu395.C, Leu396.C, Phe433.C, Gln437.C, Met441.C, Ile535.D, Leu536.D | |
| H | -13.6 | Ile535.B, Leu536.B, Ile388.D, Leu391.D, Val392.D, Leu395.D, Leu396.D, Gln437.D, Met441.D | |
| I | -13.2 | Leu521.A, Gly522.A, Asp523.A, Leu521.B, Gly522.B, Asp523.B, Leu521.C, Gly522.C, Asp523.C, Leu521.D, Gly522.D | |
| J | -13.6 | Ile388.A, Leu391.A, Val392.A, Leu395.A, Leu396.A, Phe433.A, Gln437.A, Met441.A, Ile535.C, Leu536.C | |
| K | -12.6 | Arg534.B, Ile535.B, Pro538.B, Ala539.B, Phe485.D, Phe489.D, Ile510.D, Phe514.D | |
| L | -12.4 | Phe485.C, Ile510.C, Phe514.C, Arg534.D, Ile535.D, Pro538.D, Ala539.D, Val542.D | |
| M | -16.6 | Tyr496.A, Phe509.A, Ile108.B, Leu111.B, Val112.B, Tyr119.B, Ser124.B, Trp450.B | |
| N | -16.6 | Tyr496.B, Phe509.B, Ile108.D, Leu111.D, Val112.D, Tyr119.D, Ser124.D, Trp450.D | |
| O | -13.6 | Ile535.A, Leu536.A, Ile388.B, Leu391.B, Val392.B, Leu395.B, Leu396.B, Phe433.B, Gln437.B, Met441.B | |
| P | -12.4 | Arg534.A, Ile535.A, Pro538.A, Ala539.A, Val542.A, Phe485.B, Ile510.B, Phe514.B | |
| Q | -12.4 | Phe485.A, Ile510.A, Phe514.A, Arg534.C, Ile535.C, Pro538.C, Ala539.C, Val542.C | |
| 6du8_IC | E | -13.9 | Ala481.C, Phe484.C, Phe485.C, Ile513.C, Phe514.C, Phe517.C, Met555.C, Ile559.C, Val542.D, Phe546.D, Phe549.D, Leu553.D |
| F | -13.8 | Val542.B, Phe546.B, Phe549.B, Ala481.D, Phe484.D, Phe485.D, Ile513.D, Phe514.D, Phe517.D, Met555.D, Ile559.D | |
| G | -13.0 | Phe556.A, Ile519.B, Ile520.B, Leu521.B, Gly522.B, Phe524.B, Phe549.B, Leu552.B, Leu553.B, Phe556.B, Leu521.D, Phe556.D | |
| H | -12.9 | Val444.C, Phe447.C, Phe448.C, Ile451.C, Met483.D, Val487.D, Tyr491.D, Leu494.D, Leu536.D, Ala539.D, Thr543.D, Phe547.D, Phe550.D | |
| I | -12.7 | Ile385.A, Trp386.A, Phe447.A, Phe448.A, Ile451.A, Tyr491.C, Leu536.C, Ala539.C, Tyr540.C, Thr543.C | |
| J | -13.5 | Ile519.A, Ile520.A, Leu521.A, Gly522.A, Val545.A, Phe549.A, Leu552.A, Phe556.A, Leu521.B, Phe549.C, Leu553.C, Phe556.C | |
| K | -13.9 | Val542.A, Phe546.A, Phe549.A, Ala481.B, Phe484.B, Phe485.B, Ile513.B, Phe514.B, Phe517.B, Met555.B, Ile559.B | |
| L | -13.8 | Ala481.A, Phe484.A, Phe485.A, Ile513.A, Phe514.A, Phe517.A, Met555.A, Ile559.A, Val542.C, Phe546.C, Phe549.C | |
| M | -12.9 | Ile519.A, Ile520.A, Leu521.A, Gly522.A, Phe524.A, Phe549.A, Leu552.A, Leu553.A, Phe556.A, Leu521.B, Phe556.B | |
| N | -12.9 | Met483.A, Val487.A, Tyr491.A, Leu494.A, Leu536.A, Ala539.A, Thr543.A, Phe547.A, Phe550.A, Val444.B, Phe447.B, Phe448.B, Ile451.B | |
| O | -13.4 | Leu521.A, Ile519.C, Ile520.C, Leu521.C, Gly522.C, Val545.C, Phe549.C, Leu552.C, Leu553.C, Phe556.C, Phe549.D, Leu553.D, Phe556.D | |
| P | -12.9 | Met483.B, Val487.B, Tyr491.B, Leu494.B, Leu536.B, Ala539.B, Thr543.B, Phe547.B, Phe550.B, Val444.D, Phe447.D, Phe448.D, Ile451.D | |
| TRPV1 | |||
| TRPV1, closed, Rat 3j5p | |||
| 3j5p_EC | E | -14.0 | Phe517.B, Val518.B, Leu521.B, Phe522.B, Val525.B, Leu529.B, Arg534.B, Glu536.B |
| F | -14.0 | Phe517.D, Val518.D, Leu521.D, Phe522.D, Val525.D, Leu529.D, Arg534.D, Glu536.D | |
| G | -14.0 | Phe517.A, Val518.A, Leu521.A, Phe522.A, Val525.A, Leu529.A, Arg534.A, Glu536.A | |
| H | -14.0 | Phe517.C, Val518.C, Leu521.C, Phe522.C, Val525.C, Leu529.C, Arg534.C, Glu536.C | |
| 3j5p_IC | E | -13.4 | Phe496.D, Val508.D, Ile514.D, Phe517.D, Val518.D, Leu521.D, Phe522.D, Val525.D |
| F | -13.4 | Phe496.B, Val508.B, Ile514.B, Phe517.B, Val518.B, Leu521.B, Phe522.B, Val525.B | |
| G | -13.4 | Phe496.C, Val508.C, Ile514.C, Phe517.C, Val518.C, Leu521.C, Phe522.C, Val525.C | |
| H | -13.2 | Phe496.A, Val508.A, Ile514.A, Phe517.A, Val518.A, Leu521.A, Phe522.A, Val525.A | |
| TRPV1, open, with DkTx and RTX, Rat 3j5q | |||
| 3j5q_EC | A | -13.6 | Val658.D, Phe517.G, Leu521.G, Phe522.G, Val525.G, Leu529.G, Glu536.G, Ala539.G, Ser540.G, Phe54 |
| C | -13.5 | Phe517.E, Leu521.E, Phe522.E, Val525.E, Leu529.E, Glu536.E, Ala539.E, Ser540.E, Phe543.E, | |
| F | -13.5 | Phe517.B, Leu521.B, Phe522.B, Val525.B, Leu529.B, Glu536.B, Ala539.B, Ser540.B, Phe543.B, | |
| H | -13.6 | Val658.B, Phe517.D, Leu521.D, Phe522.D, Val525.D, Leu529.D, Glu536.D, Ala539.D, Ser540.D, Phe54 | |
| 3j5q_IC | A | -14.0 | Val508.B, Tyr511.B, Ile514.B, Leu515.B, Val518.B, Phe543.B, Met547.B, Leu574.B, Ala665.E |
| C | -13.7 | Val508.E, Tyr511.E, Ile514.E, Leu515.E, Val518.E, Phe543.E, Met547.E, Leu574.E, Leu662.G, Ala665.G | |
| F | -13.6 | Gly643.B, Tyr671.B, Asn676.B, Ile679.B, Ala680.B, Tyr671.D, Ile679.D, Ala680.D, Gly643.E, Tyr671.E, Ile679.E, Gly643.G, Tyr671.G, Ile679.G | |
| H | -13.1 | Phe438.B, Ile446.B, Met552.B, Thr556.B, Phe559.B, Met562.B, Phe582.E, Val586.E, Phe589.E | |
| I | -13.1 | Phe582.B, Val586.B, Phe589.B, Phe438.D, Ile446.D, Met552.D, Thr556.D, Phe559.D, Met562.D | |
| J | -12.8 | Phe438.E, Ile446.E, Met552.E, Thr556.E, Phe559.E, Met562.E, Phe582.G, Phe589.G | |
| K | -13.7 | Ala665.D, Val508.G, Tyr511.G, Ile514.G, Leu515.G, Val518.G, Phe543.G, Met547.G, Leu574.G | |
| L | -13.2 | Leu662.B, Ala665.B, Val508.D, Tyr511.D, Ile514.D, Leu515.D, Met547.D, Ile573.D, Leu574.D | |
| M | -13.0 | Phe582.D, Phe589.D, Phe438.G, Ile446.G, Met552.G, Thr556.G, Phe559.G, Met562.G | |
| TRPV1, activated intermdeiate, with capsaicin, Rat 3j5r | |||
| 3j5r_EC | E | -15.2 | Val518.C, Leu521.C, Phe522.C, Val525.C, Leu529.C, Arg534.C, Glu536.C, Ser540.C |
| F | -14.9 | Val518.A, Phe522.A, Val525.A, Leu529.A, Arg534.A, Glu536.A, Ser540.A, Phe543.A | |
| G | -14.9 | Val518.B, Leu521.B, Phe522.B, Val525.B, Leu529.B, Arg534.B, Glu536.B, Ser540.B | |
| H | -14.8 | Val518.D, Leu521.D, Phe522.D, Val525.D, Leu529.D, Arg534.D, Glu536.D, Ser540.D | |
| 3j5r_IC | [none] | ||
| TRPV1, closed, Rat 3j9j | |||
| 3j9j_EC | E | -13.7 | Phe209.A, Phe58.B, Cys62.B, Ile66.B, Tyr73.B, Tyr74.B, Trp169.B, Met172.B |
| F | -13.6 | Val106.C, Phe109.C, Phe110.C, Leu144.C, Val147.C, Val148.C, Phe151.C, Ser152.C | |
| G | -13.5 | Val106.A, Phe109.A, Phe110.A, Leu144.A, Val147.A, Val148.A, Phe151.A, Ser152.A | |
| H | -13.5 | Phe109.A, Ile113.A, Phe137.A, Leu141.A, Val145.A, Val148.A, Leu149.A, Arg154.A | |
| I | -13.2 | Phe59.B, Leu63.B, Ile66.B, Ile67.B, Ala70.B, Tyr74.B, Phe93.B, Leu100.B | |
| J | -13.8 | Leu141.A, Phe142.A, Val145.A, Glu156.A, Ala159.A, Ser160.A, Phe252.C, Val255.C | |
| K | -13.5 | Phe109.C, Ile113.C, Phe137.C, Leu141.C, Val145.C, Val148.C, Leu149.C, Arg154.C | |
| L | -13.8 | Leu141.C, Phe142.C, Val145.C, Glu156.C, Ala159.C, Ser160.C, Phe252.D, Val255.D | |
| M | -13.8 | Phe58.C, Cys62.C, Ile66.C, Tyr73.C, Tyr74.C, Trp169.C, Met172.C, Phe209.D | |
| N | -12.9 | Ile66.A, Tyr73.A, Tyr74.A, Trp169.A, Met172.A, Leu205.C, Val206.C, Phe209.C, Leu227.C | |
| O | -13.1 | Phe59.C, Leu63.C, Ile66.C, Ile67.C, Ala70.C, Tyr74.C, Phe93.C, Leu100.C | |
| P | -13.1 | Phe59.D, Leu63.D, Ile66.D, Ile67.D, Ala70.D, Tyr74.D, Phe93.D, Arg94.D, Leu100.D | |
| Q | -13.6 | Val106.B, Phe109.B, Phe110.B, Leu144.B, Val147.B, Val148.B, Phe151.B, Ser152.B | |
| R | -13.6 | Val106.D, Phe109.D, Phe110.D, Leu144.D, Val147.D, Val148.D, Phe151.D, Ser152.D | |
| S | -13.6 | Phe109.B, Ile113.B, Phe137.B, Leu141.B, Val145.B, Val148.B, Leu149.B, Arg154.B | |
| T | -13.4 | Phe109.D, Ile113.D, Phe137.D, Leu141.D, Val145.D, Val148.D, Leu149.D, Arg154.D | |
| U | -13.9 | Phe252.B, Val255.B, Val138.D, Leu141.D, Phe142.D, Val145.D, Leu149.D, Glu156.D, Ala159.D, Ser160.D, Phe163.D | |
| V | -13.8 | Phe252.A, Val255.A, Leu141.B, Phe142.B, Val145.B, Glu156.B, Ala159.B, Ser160.B | |
| W | -12.7 | Phe209.B, Leu227.B, Phe59.D, Cys62.D, Ile66.D, Thr69.D, Tyr73.D, Tyr74.D | |
| 3j9j_IC | E | -15.0 | Phe109.A, Ile113.A, Phe116.A, Leu117.A, Arg120.A, Pro121.A, Ser122.A, Phe137.A |
| F | -14.2 | Phe109.C, Ile113.C, Phe116.C, Leu117.C, Arg120.C, Pro121.C, Phe137.C, Leu141.C, Leu144.C, Val145.C, Val148.C | |
| G | -13.7 | Ile53.C, Phe56.C, Asn57.C, Val60.C, Ile99.C, Leu100.C, Ser103.C, Tyr107.C | |
| H | -13.6 | Ile53.B, Phe56.B, Asn57.B, Val60.B, Ile99.B, Leu100.B, Ser103.B, Tyr107.B, Phe309.B | |
| I | -13.6 | Ile53.A, Phe56.A, Asn57.A, Val60.A, Ile99.A, Leu100.A, Ser103.A, Tyr107.A | |
| J | -14.2 | Phe109.B, Ile113.B, Phe116.B, Leu117.B, Arg120.B, Pro121.B, Phe137.B, Leu141.B, Leu144.B, Val145.B, Val148.B | |
| K | -14.2 | Phe109.D, Ile113.D, Phe116.D, Leu117.D, Arg120.D, Pro121.D, Phe137.D, Leu141.D, Leu144.D, Val145.D, Val148.D | |
| L | -13.6 | Ile53.D, Phe56.D, Asn57.D, Val60.D, Ile99.D, Leu100.D, Ser103.D, Tyr107.D | |
| TRPV1, open, with DkTx and RTX, Rat 5irx | |||
| 5irx_EC | G | -15.0 | Gly643.A, Met644.A, Gly645.A, Tyr671.A, Gly643.B, Met644.B, Asp646.B, Gly643.C, Met644.C, Tyr671.C, Ile679.C, Gly643.D, Met644.D, Tyr671.D |
| H | -14.2 | Phe582.B, Leu585.B, Val586.B, Phe589.B, Leu630.B, Tyr631.B, Glu26.F, Phe27.F, Ile28.F | |
| I | -14.5 | Ile446.A, Ala450.A, Tyr453.A, Tyr454.A, Trp549.A, Met552.A, Phe589.B, Leu630.B | |
| J | -13.3 | Phe582.A, Phe589.A, Leu630.A, Ile446.C, Tyr453.C, Tyr454.C, Trp549.C, Met552.C | |
| K | -14.9 | Phe582.C, Leu585.C, Val586.C, Phe589.C, Leu630.C, Tyr631.C, Met552.D, Glu26.E, Phe27.E | |
| L | -14.5 | Phe589.C, Leu630.C, Ile446.D, Ala450.D, Tyr453.D, Tyr454.D, Trp549.D, Met552.D | |
| M | -13.4 | Ile446.B, Tyr453.B, Tyr454.B, Trp549.B, Met552.B, Phe582.D, Phe589.D, Leu630.D | |
| 5irx_IC | G | -15.9 | Gly643.A, Met644.A, Tyr671.A, Asn676.A, Ile679.A, Gly643.B, Tyr671.B, Asn676.B, Ile679.B, Gly643.C, Asn676.C, Ile679.C, Ile679.D |
| H | -14.1 | Phe582.A, Leu585.A, Val586.A, Phe589.A, Phe438.C, Met552.C, Leu553.C, Tyr555.C, Thr556.C, Phe559.C | |
| I | -13.7 | Phe436.C, Asn437.C, Val440.C, Ile479.C, Leu480.C, Ser483.C, Tyr487.C, Arg491.C | |
| J | -14.1 | Phe438.A, Met552.A, Leu553.A, Tyr555.A, Thr556.A, Phe559.A, Phe582.B, Leu585.B, Val586.B, Phe589.B | |
| K | -14.1 | Phe582.C, Leu585.C, Val586.C, Phe589.C, Phe438.D, Met552.D, Leu553.D, Tyr555.D, Thr556.D, Phe559.D | |
| L | -14.1 | Phe438.B, Met552.B, Leu553.B, Tyr555.B, Thr556.B, Phe559.B, Phe582.D, Leu585.D, Val586.D, Phe589.D | |
| M | -13.7 | Phe436.D, Asn437.D, Val440.D, Ile479.D, Leu480.D, Ser483.D, Tyr487.D, Arg491.D | |
| TRPV1, closed, Rat 5irz | |||
| 5irz_EC | [none] | ||
| 5irz_IC | A | -13.9 | Phe436.E, Asn437.E, Val440.E, Ile479.E, Leu480.E, Ser483.E, Tyr487.E, Arg491.E |
| F | -13.9 | Phe436.C, Asn437.C, Val440.C, Ile479.C, Leu480.C, Ser483.C, Tyr487.C, Arg491.C | |
| G | -13.9 | Phe436.D, Asn437.D, Val440.D, Ile479.D, Leu480.D, Ser483.D, Tyr487.D, Arg491.D | |
| H | -13.8 | Phe436.B, Asn437.B, Val440.B, Ile479.B, Leu480.B, Ser483.B, Tyr487.B, Arg491.B | |
| TRPV1, closed, with capsazepine, Rat 5is0 | |||
| 5is0_EC | A | -12.9 | 0 Phe582.C, Phe589.C, Leu630.C, Ile446.D, Tyr453.D, Tyr454.D, Trp549.D, Met552.D |
| F | -12.9 | 0 Phe582.D, Phe589.D, Leu630.D, Ile446.E, Tyr453.E, Tyr454.E, Trp549.E, Met552.E | |
| G | -12.7 | Ala657.C, Ile660.C, Ile661.C, Leu664.C, Ala665.C, Ile668.C, Leu577.D, Met581.D, Tyr631.D | |
| H | -12.5 | Ala657.B, Ile660.B, Ile661.B, Leu664.B, Ala665.B, Ile668.B, Leu577.C, Met581.C, Tyr631.C | |
| I | -13.1 | Ile446.B, Tyr453.B, Tyr454.B, Trp549.B, Met552.B, Phe582.E, Phe589.E, Leu630.E | |
| J | -13.0 | Phe582.B, Phe589.B, Leu630.B, Ile446.C, Tyr453.C, Tyr454.C, Trp549.C, Met552.C | |
| K | -12.8 | Leu577.B, Met581.B, Tyr631.B, Ala657.E, Ile660.E, Ile661.E, Leu664.E, Ile668.E | |
| L | -12.6 | Ala657.D, Ile660.D, Ile661.D, Leu664.D, Ile668.D, Leu577.E, Met581.E, Tyr631.E | |
| 5iso_IC | A | -14.1 | Phe436.D, Asn437.D, Val440.D, Ile479.D, Leu480.D, Ser483.D, Tyr487.D, Phe488.D, Arg491.D |
| F | -13.7 | Asn437.C, Val440.C, Ile479.C, Leu480.C, Ser483.C, Tyr487.C, Phe488.C, Arg491.C | |
| G | -13.2 | Ile433.B, Phe436.B, Asn437.B, Val440.B, Ile479.B, Leu480.B, Ser483.B, Tyr487.B | |
| TRPV2 | |||
| TRPV2, closed, Rabbit 5an8 | |||
| 5an8_EC | [none] | ||
| 5an8_IC | E | -14.3 | Leu540.A, Leu543.A, Val544.A, Phe547.A, Phe395.C, Leu510.C, Leu511.C, Tyr513.C, Thr514.C, Arg515.C, Phe517.C, Gln518.C |
| F | -14.0 | Phe395.A, Leu399.A, Leu403.A, Leu510.A, Thr514.A, Phe517.A, Gln518.A, Arg537.B, Leu540.B | |
| G | -14.0 | Arg537.C, Leu540.C, Phe395.D, Leu399.D, Leu403.D, Leu510.D, Thr514.D, Phe517.D, Gln518.D | |
| H | -14.3 | Phe395.B, Leu510.B, Leu511.B, Tyr513.B, Thr514.B, Phe517.B, Gln518.B, Leu540.D, Leu543.D, Val544.D, Phe547.D | |
| TRPV2, open, Rat 6bo4 | |||
| 6bo4_EC | E | -17.2 | Lys602.A, Met607.A, Phe540.B, Val543.B, Tyr544.B, Leu548.B, Phe551.B, Leu555.B, Phe603.B, Thr604.B, Gly606.B, Gly608.B, Glu609.B, Leu610.B, Ala611.B, Leu626.B, Tyr629.B, Val630.B, Thr633.B, Tyr634.B, Leu638.B |
| F | -17.1 | Phe540.A, Val543.A, Tyr544.A, Phe547.A, Leu548.A, Phe551.A, Leu555.A, Phe603.A, Thr604.A, Gly608.A, Glu609.A, Leu610.A, Ala611.A, Tyr629.A, Val630.A, Thr633.A, Tyr634.A, Leu637.A, Leu638.A, Met607.D | |
| G | -17.0 | Met607.B, Phe540.C, Val543.C, Tyr544.C, Phe547.C, Leu548.C, Phe551.C, Leu555.C, Phe603.C, Thr604.C, Gly608.C, Glu609.C, Leu610.C, Ala611.C, Tyr629.C, Val630.C, Thr633.C, Tyr634.C, Leu637.C, Leu638.C | |
| H | -15.7 | Phe405.B, Val546.C, Phe549.C, Lys566.C, Asn571.C, Asn572.C, Ala588.C, Pro589.C | |
| I | -15.7 | Val546.A, Phe549.A, Lys566.A, Asn571.A, Asn572.A, Ala588.A, Pro589.A, Phe405.D | |
| J | -15.7 | Phe405.A, Val546.B, Phe549.B, Lys566.B, Asn571.B, Asn572.B, Ala588.B, Pro589.B | |
| K | -15.0 | Gly606.B, Met607.B, Leu638.B, Gly606.C, Met607.C, Tyr634.C, Val635.C, Leu638.C, Gly606.D, Met607.D, Gly608.D, Glu609.D | |
| L | -14.4 | Leu538.B, Leu541.B, Leu545.B, Pro587.B, Ala588.B, Tyr590.B, Leu594.B, Leu598.B, Leu624.C | |
| M | -14.1 | Leu538.C, Leu541.C, Leu545.C, Pro587.C, Ala588.C, Tyr590.C, Leu594.C, Leu598.C, Leu623.D, Leu624.D | |
| N | -14.1 | Leu541.A, Leu545.A, Phe549.A, Pro587.A, Ala588.A, Tyr590.A, Leu594.A, Leu598.A, Leu623.B, Leu624.B | |
| O | -17.4 | Met607.C, Phe540.D, Val543.D, Tyr544.D, Leu548.D, Phe551.D, Leu555.D, Phe603.D, Thr604.D, Gly606.D, Gly608.D, Glu609.D, Leu610.D, Ala611.D, Leu626.D, Tyr629.D, Val630.D, Thr633.D, Tyr634.D, Leu638.D | |
| P | -15.8 | Phe405.C, Val546.D, Phe549.D, Lys566.D, Asn571.D, Asn572.D, Ala588.D, Pro589.D | |
| Q | -16.4 | Gly606.A, Tyr634.A, Leu638.A, Gly606.B, Met607.B, Tyr634.B, Val635.B, Leu638.B, Gly606.C, Met607.C, Gly608.C, Glu609.C | |
| R | -14.0 | Leu623.A, Leu624.A, Leu627.A, Leu538.D, Leu541.D, Leu545.D, Glu586.D, Pro587.D, Ala588.D, Tyr590.D, Leu594.D, Leu598.D | |
| 6bo4_IC | E | -15.0 | Phe462.A, Ile463.A, Trp464.A, Ile465.A, Ser466.A, Phe467.A, Met468.A, Ile474.A, Gln583.A |
| F | -14.6 | Leu538.A, Arg539.A, Leu541.A, Leu542.A, Leu545.A, Val546.A, Phe549.A, Phe519.D, Thr522.D | |
| G | -14.5 | Phe519.B, Thr522.B, Phe467.C, Leu538.C, Arg539.C, Leu541.C, Leu542.C, Leu545.C, Val546.C, Phe549.C | |
| H | -14.4 | Phe405.A, Trp509.A, Phe519.A, Thr522.A, Phe467.B, Leu538.B, Arg539.B, Leu542.B, Val546.B, Phe549.B | |
| I | -14.7 | Phe462.C, Ile463.C, Trp464.C, Ile465.C, Ser466.C, Phe467.C, Met468.C, Ile474.C, Gln583.C | |
| J | -13.7 | Phe462.B, Ile463.B, Trp464.B, Ile465.B, Ser466.B, Phe467.B, Met468.B, Ile474.B, Gln583.B | |
| K | -15.1 | Phe462.D, Ile463.D, Trp464.D, Ile465.D, Ser466.D, Phe467.D, Met468.D, Ile474.D, Gln583.D | |
| L | -14.5 | Phe519.C, His521.C, Thr522.C, Leu538.D, Arg539.D, Leu541.D, Leu542.D, Leu545.D, Val546.D, Phe549.D | |
| TRPV2, partially close, Rat 6bo5 | |||
| 6bo5_EC | E | -12.5 | Leu542.A, Leu545.A, Val546.A, Phe549.A, Leu598.A, Phe601.A, Gly620.B, Val621.B, Leu624.B |
| F | -12.5 | Gly620.A, Val621.A, Leu624.A, Leu542.D, Leu545.D, Val546.D, Phe549.D, Leu598.D, Phe601.D | |
| G | -12.3 | Leu478.A, Leu482.A, Trp496.A, Pro499.A, Leu500.A, Leu503.A, Phe618.B, Val621.B | |
| H | -12.3 | Phe618.A, Val621.A, Leu478.D, Leu482.D, Trp496.D, Pro499.D, Leu500.D, Leu503.D | |
| I | -12.5 | Leu542.C, Leu545.C, Val546.C, Phe549.C, Leu598.C, Phe601.C, Gly620.D, Val621.D, Leu624.D | |
| J | -12.5 | Leu542.B, Leu545.B, Val546.B, Phe549.B, Leu598.B, Phe601.B, Gly620.C, Val621.C, Leu624.C | |
| K | -12.3 | Leu478.B, Leu482.B, Trp496.B, Pro499.B, Leu500.B, Leu503.B, Phe618.C, Val621.C | |
| L | -12.3 | Leu478.C, Leu482.C, Trp496.C, Pro499.C, Leu500.C, Leu503.C, Phe618.D, Val621.D | |
| 6bo5_IC | E | -15.6 | Phe397.A, Leu401.A, Phe405.A, Thr408.A, Trp509.A, Phe519.A, Thr522.A, Arg539.B, Leu542.B, Val546.B, Phe549.B |
| F | -15.5 | Phe397.C, Leu401.C, Phe405.C, Thr408.C, Trp509.C, Phe519.C, Thr522.C, Arg539.D, Leu542.D, Val546.D, Phe549.D | |
| G | -15.5 | Arg539.A, Leu542.A, Val546.A, Phe549.A, Phe397.D, Leu401.D, Phe405.D, Thr408.D, Trp509.D, Phe519.D, Thr522.D | |
| H | -14.5 | Phe456.D, Arg460.D, Leu461.D, Phe462.D, Ile463.D, Leu477.D, Leu478.D, Leu481.D | |
| I | -14.2 | Phe456.A, Arg460.A, Leu461.A, Phe462.A, Ile463.A, Leu477.A, Leu481.A, Leu485.A | |
| J | -13.4 | Ser466.B, Phe467.B, Met468.B, Tyr471.B, Leu538.B, Leu541.B, Leu542.B, Leu545.B, Phe549.B | |
| K | -13.3 | Ser466.D, Phe467.D, Met468.D, Tyr471.D, Leu538.D, Leu541.D, Leu542.D, Leu545.D, Phe549.D | |
| L | -13.8 | Ser466.A, Phe467.A, Met468.A, Tyr471.A, Ile474.A, Leu538.A, Leu541.A, Leu624.B, Leu625.B | |
| M | -15.5 | Phe397.B, Leu401.B, Phe405.B, Thr408.B, Trp509.B, Phe519.B, Thr522.B, Arg539.C, Leu542.C, Val546.C, Phe549.C | |
| N | -14.4 | Phe456.B, Arg460.B, Leu461.B, Phe462.B, Ile463.B, Leu477.B, Leu478.B, Leu481.B | |
| O | -13.7 | Ser466.C, Phe467.C, Met468.C, Tyr471.C, Leu538.C, Leu541.C, Leu542.C, Leu545.C | |
| TRPV2, with Rtx, C2 symmetry, Rabbit 6bwj | |||
| 6bwj_EC | 1 | -13.5 | Phe547.C, Ile591.C, Leu403.D, Thr406.D, Ala407.D, Tyr410.D, His411.D, Trp507.D |
| 2 | -14.0 | Phe547.A, Arg589.A, Ser590.A, Ile591.A, Leu592.A, Leu399.B, Leu403.B, Tyr410.B | |
| 6bwj_IC | E | -17.7 | Asn394.C, Cys397.C, Tyr398.C, Tyr401.C, Leu438.C, Gly442.C, Tyr445.C, Leu446.C, Tyr512.C, Tyr513.C, Ser665.C, Glu668.C, Met669.C, Tyr673.C |
| F | -15.8 | Phe454.D, Arg458.D, Trp462.D, Ile463.D, Ser464.D, Phe465.D, Ile472.D, Leu475.D, Leu476.D, Leu479.D | |
| G | -14.9 | Leu451.C, Phe454.C, Trp455.C, Arg458.C, Leu459.C, Phe460.C, Leu475.C, Leu479.C, Leu483.C | |
| H | -14.6 | Leu451.D, Phe454.D, Trp455.D, Arg458.D, Leu459.D, Leu475.D, Leu479.D, Leu483.D | |
| I | -14.0 | Phe460.C, Trp462.C, Ile463.C, Ser464.C, Phe465.C, Ile472.C, Leu476.C, Leu479.C, Leu480.C, Leu483.C | |
| J | -17.7 | Asn394.A, Cys397.A, Tyr398.A, Tyr401.A, Leu438.A, Gly442.A, Tyr445.A, Leu446.A, Tyr512.A, Tyr513.A, Ser665.A, Glu668.A, Met669.A, Tyr673.A | |
| K | -15.8 | Phe454.B, Trp462.B, Ile463.B, Ser464.B, Phe465.B, Ile472.B, Leu475.B, Leu476.B, Leu479.B | |
| L | -14.9 | Leu451.A, Phe454.A, Trp455.A, Arg458.A, Leu459.A, Phe460.A, Leu475.A, Leu479.A, Leu483.A | |
| M | -14.6 | Leu451.B, Phe454.B, Trp455.B, Arg458.B, Leu459.B, Leu475.B, Leu479.B, Leu483.B | |
| N | -14.0 | Phe460.A, Trp462.A, Ile463.A, Ser464.A, Phe465.A, Ile472.A, Leu476.A, Leu479.A, Leu480.A, Leu483.A | |
| TRPV2, Ca bound, C2 symmetry, Rabbit 6bwm | |||
| 6bwm_EC | E | -13.8 | Phe393.C, Leu396.C, Val400.C, Ile404.C, Met431.C, Leu434.C, Gly435.C, Leu438.C |
| F | -13.6 | Leu614.A, Arg615.A, Gly618.A, Leu622.A, Leu539.B, Leu540.B, Leu543.B, Leu592.B | |
| G | -13.4 | Leu614.C, Arg615.C, Gly618.C, Leu622.C, Leu539.D, Leu540.D, Leu543.D, Leu592.D | |
| H | -13.0 | Leu403.A, Thr406.A, Ala407.A, Tyr410.A, His411.A, Trp507.A, Leu540.D, Leu543.D, Val544.D, Phe547.D | |
| I | -12.8 | Leu396.D, Val400.D, Leu403.D, Ile404.D, Ala407.D, Met431.D, Leu432.D, Gly435.D | |
| J | -12.4 | Leu540.B, Phe547.B, Ile591.B, Leu399.C, Leu403.C, Thr406.C, Tyr410.C, Trp507.C | |
| K | -13.6 | Phe393.A, Leu396.A, Val400.A, Ile404.A, Met431.A, Leu434.A, Gly435.A, Leu438.A | |
| L | -12.6 | Leu396.B, Leu399.B, Val400.B, Leu403.B, Ile404.B, Met431.B, Leu432.B, Gly435.B | |
| 6bwm_IC | E | -17.4 | Asn394.C, Cys397.C, Tyr398.C, Tyr401.C, Leu438.C, Tyr445.C, Leu446.C, Trp452.C, Tyr453.C, Glu668.C, Met669.C, Asn671.C, Gly672.C, Tyr673.C |
| F | -15.0 | Leu540.C, Val544.C, Phe391.D, Phe395.D, Tyr513.D, Thr514.D, Arg515.D, Gly516.D, Phe517.D, Thr520.D | |
| G | -16.9 | Arg390.C, Phe393.C, Asn394.C, Leu441.C, Tyr445.C, Gly672.C, Trp674.C, Trp675.C, Arg678.C | |
| H | -18.0 | Asn394.A, Cys397.A, Tyr398.A, Tyr401.A, Tyr445.A, Leu446.A, Trp452.A, Tyr453.A, Glu668.A, Met669.A, Asn671.A, Gly672.A, Tyr673.A | |
| I | -17.4 | Arg390.A, Phe393.A, Asn394.A, Cys397.A, Leu438.A, Tyr445.A, Glu668.A, Met669.A, Asn671.A, Gly672.A, Tyr673.A, Trp674.A | |
| J | -15.4 | Leu540.A, Val544.A, Phe391.B, Phe395.B, Tyr513.B, Thr514.B, Arg515.B, Gly516.B, Phe517.B, Thr520.B | |
| TRPV3 | |||
| TRPV3, with bromo 2-APB, Mouse 6dvy | |||
| 6dvy_EC | E | -15.5 | Phe447.D, Phe450.D, Ile453.D, Thr454.D, Leu457.D, Val458.D, Leu482.D, Gln483.D, Leu485.D, Gly486.D |
| F | -15.5 | Phe447.A, Phe450.A, Ile453.A, Thr454.A, Leu457.A, Val458.A, Leu482.A, Gln483.A, Leu485.A, Gly486.A | |
| G | -15.5 | Phe447.C, Phe450.C, Ile453.C, Thr454.C, Leu457.C, Val458.C, Leu482.C, Gln483.C, Leu485.C, Gly486.C, Arg487.C | |
| H | -13.3 | Phe449.A, Ile453.A, Thr456.A, Leu457.A, Tyr460.A, Tyr461.A, Leu588.D, Phe592.D, Ile595.D, Leu599.D, Phe625.D | |
| I | -13.2 | Leu588.C, Phe592.C, Ile595.C, Leu599.C, Phe625.C, Phe449.D, Ile453.D, Thr456.D, Leu457.D, Tyr460.D, Tyr461.D | |
| J | -13.1 | Leu588.B, Phe592.B, Ile595.B, Leu599.B, Phe625.B, Phe449.C, Ile453.C, Thr456.C, Leu457.C, Tyr460.C, Tyr461.C | |
| K | -15.5 | Phe447.B, Phe450.B, Ile453.B, Thr454.B, Leu457.B, Val458.B, Leu482.B, Gln483.B, Leu485.B, Gly486.B, Arg487.B | |
| L | -13.3 | Leu588.A, Phe592.A, Ile595.A, Leu599.A, Phe625.A, Phe449.B, Ile453.B, Thr456.B, Leu457.B, Tyr460.B, Tyr461.B | |
| 6dvy_IC | [none] | ||
| TRPV3, closed, Human 6mho | |||
| 6mho_EC | E | -13.7 | Phe449.B, Tyr460.B, Tyr461.B, Trp559.B, Phe592.C, Val596.C, Leu599.C, Val603.C, Phe625.C |
| F | -13.5 | Phe592.A, Val596.A, Leu599.A, Val603.A, Phe625.A, Phe449.D, Tyr460.D, Tyr461.D, Trp559.D | |
| G | -13.5 | Phe449.C, Tyr460.C, Tyr461.C, Trp559.C, Met562.C, Phe592.D, Val596.D, Leu599.D, Val603.D, Phe625.D | |
| H | -13.3 | Tyr544.C, Glu546.C, Ala549.C, Leu553.C, Tyr650.D, Ile652.D, Leu653.D, Phe656.D | |
| I | -13.2 | Leu591.A, Ile595.A, Ser626.A, Asp627.A, Leu630.A, Ile652.B, Leu655.B, Phe656.B, Ile659.B | |
| J | -13.1 | Ile652.A, Leu655.A, Phe656.A, Ile659.A, Leu591.D, Ile595.D, Ser626.D, Leu630.D | |
| K | -12.9 | Tyr650.A, Ile652.A, Leu653.A, Phe656.A, Tyr544.D, Glu546.D, Ala549.D, Leu553.D | |
| L | -12.8 | Phe590.C, Leu591.C, Tyr594.C, Ile595.C, Leu598.C, Ser626.C, Leu630.C, Phe633.C, Ile652.D, Leu655.D, Phe656.D, Ile659.D, Ile663.D | |
| M | -13.9 | Phe449.A, Tyr460.A, Tyr461.A, Trp559.A, Met562.A, Phe592.B, Val596.B, Leu599.B, Val603.B, Phe625.B | |
| N | -13.6 | Tyr544.A, Glu546.A, Ala549.A, Leu553.A, Tyr650.B, Ile652.B, Leu653.B, Phe656.B | |
| O | -13.4 | Tyr544.B, Glu546.B, Ala549.B, Leu553.B, Tyr650.C, Ile652.C, Leu653.C, Phe656.C | |
| P | -13.1 | Leu591.B, Ser626.B, Asp627.B, Leu630.B, Ile652.C, Leu655.C, Phe656.C, Ile659.C | |
| Q | -12.8 | Phe590.C, Leu591.C, Tyr594.C, Ile595.C, Leu598.C, Ser626.C, Leu630.C, Phe633.C, Ile652.D, Leu655.D, Phe656.D, Ile659.D, Ile663.D | |
| 6mho_IC | E | -13.2 | Ile505.C, Phe506.C, Leu508.C, Phe527.C, Ile528.C, Val531.C, Leu532.C, Leu535.C |
| F | -13.2 | Phe447.D, Met488.D, Phe489.D, Ile492.D, Trp493.D, Cys496.D, Lys500.D, Met706.D | |
| G | -13.0 | Ile505.D, Phe506.D, Phe527.D, Ile528.D, Val531.D, Leu532.D, Leu535.D, Cys550.D | |
| H | -12.8 | Trp521.C, Gln580.C, Ile583.C, Leu584.C, Leu588.C, Leu591.C, Ile595.C, Ile659.D, Ile663.D | |
| I | -12.4 | Val499.C, Gly502.C, Ile503.C, Phe506.C, Phe527.C, Val531.C, Ile534.C, Leu535.C | |
| J | -13.2 | Phe447.C, Met488.C, Phe489.C, Ile492.C, Trp493.C, Cys496.C, Lys500.C, Met706.C | |
| K | -12.6 | Ser498.D, Val499.D, Gly502.D, Ile503.D, Phe506.D, Phe527.D, Val531.D, Ile534.D, Leu535.D | |
| L | -13.5 | Trp521.A, Gln580.A, Ile583.A, Leu584.A, Leu588.A, Leu591.A, Ile595.A, Ile659.B, Ile663.B | |
| M | -13.2 | Phe447.B, Met488.B, Phe489.B, Ile492.B, Trp493.B, Cys496.B, Lys500.B, Met706.B | |
| N | -13.1 | Ile505.A, Phe506.A, Phe527.A, Ile528.A, Val531.A, Leu532.A, Leu535.A, Cys550.A | |
| O | -13.0 | Ile505.B, Phe506.B, Phe527.B, Ile528.B, Val531.B, Leu532.B, Leu535.B, Cys550.B | |
| P | -13.0 | Trp521.B, Gln580.B, Ile583.B, Leu584.B, Leu588.B, Leu591.B, Ile595.B, Ile659.C, Ile663.C | |
| Q | -12.6 | Met495.B, Ser498.B, Val499.B, Gly502.B, Ile503.B, Phe527.B, Ile534.B, Leu535.B, Phe538.B | |
| R | -12.5 | Ser498.A, Val499.A, Gly502.A, Ile503.A, Phe527.A, Ile534.A, Leu535.A, Phe538.A | |
| TRPV3, with 2-APB, Human 6mhs | |||
| 6mhs_EC | E | -15.2 | Phe592.A, Val596.A, Leu599.A, Val603.A, Phe625.A, Phe449.D, Leu457.D, Tyr460.D, Tyr461.D, Trp559.D, Met562.D |
| F | -15.1 | Phe449.C, Leu457.C, Tyr460.C, Tyr461.C, Trp559.C, Phe592.D, Val596.D, Leu599.D, Val603.D, Phe625.D | |
| G | -15.1 | Phe449.B, Leu457.B, Tyr460.B, Tyr461.B, Trp559.B, Met562.B, Phe592.C, Val596.C, Leu599.C, Val603.C, Phe625.C | |
| H | -13.7 | Leu591.A, Ile595.A, Ser626.A, Val629.A, Leu630.A, Ile644.B, Ile652.B, Leu655.B, Phe656.B | |
| I | -13.7 | Ile644.A, Ile652.A, Leu655.A, Phe656.A, Leu591.D, Ile595.D, Ser626.D, Val629.D, Leu630.D | |
| J | -13.7 | Leu591.C, Ile595.C, Ser626.C, Val629.C, Leu630.C, Ile644.D, Ile652.D, Leu655.D, Phe656.D | |
| K | -15.2 | Phe449.A, Leu457.A, Tyr460.A, Tyr461.A, Trp559.A, Met562.A, Phe592.B, Val596.B, Leu599.B, Val603.B, Phe625.B | |
| L | -13.7 | Leu591.B, Ile595.B, Ser626.B, Val629.B, Leu630.B, Ile644.C, Ile652.C, Leu655.C, Phe656.C, Ile659.C | |
| 6mhs_IC | E | -14.9 | Phe656.A, Ile659.A, Thr660.A, Ile663.A, Leu664.A, Ser518.D, Trp521.D, Gln580.D, Ile583.D, Leu588.D |
| F | -14.8 | Ser518.C, Trp521.C, Gln580.C, Ile583.C, Leu588.C, Phe656.D, Ile659.D, Thr660.D, Ile663.D, Leu664.D | |
| G | -13.0 | Phe601.A, Thr660.A, Leu664.A, Ser518.D, Trp521.D, Ala556.D, Leu557.D, Ala560.D, Gln580.D, Ile583.D, Leu584.D, Leu588.D | |
| H | -13.0 | Trp521.C, Ala556.C, Leu557.C, Ala560.C, Gln580.C, Ile583.C, Leu584.C, Leu588.C, Phe601.D, Thr660.D, Leu664.D | |
| I | -12.5 | Phe656.A, Ser571.C, Met572.C, Leu588.D, Lys589.D, Leu591.D, Phe592.D, Ile595.D | |
| J | -12.5 | Leu588.A, Lys589.A, Leu591.A, Phe592.A, Ile595.A, Phe656.B, Ser571.D, Met572.D | |
| K | -12.5 | Ser571.B, Met572.B, Leu588.C, Lys589.C, Leu591.C, Phe592.C, Ile595.C, Phe656.D | |
| L | -14.9 | Ser518.A, Trp521.A, Gln580.A, Ile583.A, Leu588.A, Phe656.B, Ile659.B, Thr660.B, Ile663.B, Leu664.B | |
| M | -14.8 | Ser518.B, Trp521.B, Gln580.B, Ile583.B, Leu588.B, Phe656.C, Ile659.C, Thr660.C, Ile663.C, Leu664.C | |
| N | -13.0 | Ser518.B, Trp521.B, Ala556.B, Leu557.B, Ala560.B, Gln580.B, Ile583.B, Leu584.B, Leu588.B, Phe601.C, Thr660.C, Leu664.C | |
| O | -13.0 | Trp521.A, Ala556.A, Leu557.A, Ala560.A, Gln580.A, Ile583.A, Leu584.A, Leu588.A, Phe601.B, Thr660.B, Leu664.B | |
| P | -12.5 | Ser571.A, Met572.A, Leu588.B, Lys589.B, Leu591.B, Phe592.B, Ile595.B, Phe656.C | |
| TRPV3, with 2-APB, Human 6mhv | |||
| 6mhv_EC | E | -14.5 | Phe592.A, Val596.A, Leu599.A, Val603.A, Phe625.A, Phe449.D, Tyr460.D, Tyr461.D, Trp559.D, Met562.D |
| F | -14.5 | Phe449.A, Tyr460.A, Tyr461.A, Trp559.A, Met562.A, Phe592.B, Val596.B, Leu599.B, Val603.B, Phe625.B | |
| G | -14.5 | Phe449.C, Tyr460.C, Tyr461.C, Trp559.C, Met562.C, Phe592.D, Val596.D, Leu599.D, Val603.D, Phe625.D | |
| H | -12.8 | Ile644.A, Ile652.A, Leu655.A, Phe656.A, Ile659.A, Leu591.D, Ile595.D, Ser626.D, Asp627.D, Leu630.D | |
| I | -12.8 | Leu591.A, Ile595.A, Ser626.A, Leu630.A, Ile644.B, Ile652.B, Leu655.B, Phe656.B, Ile659.B | |
| J | -12.8 | Leu591.B, Ile595.B, Ser626.B, Asp627.B, Leu630.B, Ile644.C, Ile652.C, Leu655.C, Phe656.C, Ile659.C | |
| K | -14.5 | Phe449.B, Tyr460.B, Tyr461.B, Trp559.B, Met562.B, Phe592.C, Val596.C, Leu599.C, Val603.C, Phe625.C | |
| L | -12.8 | Leu591.C, Ile595.C, Ser626.C, Leu630.C, Ile644.D, Ile652.D, Leu655.D, Phe656.D, Ile659.D | |
| 6mhv_IC | E | -13.1 | Ser498.A, Val499.A, Gly502.A, Ile503.A, Phe527.A, Ile534.A, Leu535.A, Phe538.A |
| F | -13.1 | Ser498.D, Val499.D, Gly502.D, Ile503.D, Phe527.D, Ile534.D, Leu535.D, Phe538.D | |
| G | -12.9 | Phe569.A, Met572.A, Leu588.B, Lys589.B, Leu591.B, Phe592.B, Ile595.B, Phe656.C | |
| H | -12.9 | Phe656.A, Phe569.C, Met572.C, Leu588.D, Lys589.D, Leu591.D, Phe592.D, Ile595.D | |
| I | -12.9 | Leu588.A, Lys589.A, Leu591.A, Phe592.A, Ile595.A, Phe656.B, Phe569.D, Met572.D | |
| J | -13.0 | Ser498.C, Val499.C, Gly502.C, Ile503.C, Phe506.C, Phe527.C, Ile534.C, Leu535.C, Phe538.C | |
| K | -13.0 | Ser498.B, Val499.B, Gly502.B, Ile503.B, Phe527.B, Ile534.B, Leu535.B, Phe538.B | |
| L | -12.9 | Phe569.B, Met572.B, Leu588.C, Lys589.C, Leu591.C, Phe592.C, Ile595.C, Phe656.D | |
| TRPV3, with 2-APB, C2 symmetry, Human 6mhw | |||
| 6mhw_EC | E | -14.1 | Phe449.A, Ile453.A, Thr456.A, Leu457.A, Tyr460.A, Tyr461.A, Trp559.A, Met562.A, Phe592.B, Val596.B, Leu599.B, Val603.B |
| F | -13.6 | Phe449.B, Tyr460.B, Tyr461.B, Trp559.B, Met562.B, Phe592.C, Val596.C, Leu599.C, Val603.C | |
| G | -12.8 | Phe592.A, Leu599.A, Val603.A, Phe625.A, Phe449.D, Leu457.D, Tyr460.D, Trp559.D | |
| H | -14.9 | Phe449.C, Ile453.C, Tyr460.C, Tyr461.C, Trp559.C, Met562.C, Phe592.D, Val596.D, Leu599.D, Val603.D | |
| 6mhw_IC | E | -13.9 | Ser518.A, Trp521.A, Gln580.A, Ile583.A, Leu584.A, Leu588.A, Phe656.B, Ile659.B, Thr660.B, Ile663.B |
| F | -13.0 | Ser498.A, Val499.A, Gly502.A, Ile503.A, Phe506.A, Phe527.A, Ile534.A, Leu535.A, Phe538.A | |
| G | -12.4 | Val499.B, Gly502.B, Ile503.B, Phe506.B, Phe527.B, Val531.B, Ile534.B, Leu535.B | |
| H | -13.2 | Ser518.C, Trp521.C, Leu584.C, Leu588.C, Leu591.C, Phe656.D, Ile659.D, Thr660.D, Ile663.D | |
| I | -12.7 | Ser498.C, Val499.C, Gly502.C, Ile503.C, Phe506.C, Phe527.C, Ile534.C, Leu535.C | |
| TRPV3, with 2-APB, C2 symmetry, Human 6mhx | |||
| 6mhx_EC | E | -15.2 | Phe449.A, Ile453.A, Thr456.A, Leu457.A, Tyr460.A, Tyr461.A, Trp559.A, Met562.A, Phe592.B, Val596.B, Leu599.B, Val603.B |
| F | -15.2 | Phe449.C, Ile453.C, Thr456.C, Leu457.C, Tyr460.C, Tyr461.C, Trp559.C, Met562.C, Phe592.D, Val596.D, Leu599.D, Val603.D | |
| G | -14.4 | Phe592.A, Val596.A, Leu599.A, Phe449.D, Ile453.D, Thr456.D, Leu457.D, Tyr460.D, Tyr461.D, Trp559.D, Met562.D | |
| H | -13.2 | Ser498.A, Phe527.A, Val531.A, Ile534.A, Leu535.A, Phe538.A, Leu539.A, Tyr544.A | |
| I | -14.4 | Phe449.B, Ile453.B, Thr456.B, Leu457.B, Tyr460.B, Tyr461.B, Trp559.B, Met562.B, Phe592.C, Val596.C, Leu599.C | |
| J | -13.2 | Ser498.C, Phe527.C, Val531.C, Ile534.C, Leu535.C, Phe538.C, Leu539.C, Tyr544.C | |
| 6mhx_IC | [none] | ||
| TRPV4 | |||
| TRPV4, closed, Xenopus 6bbj | |||
| 6bbj_EC | [none] | ||
| 6bbj_IC | E | -13.7 | Leu619.B, Gly623.B, Val471.D, Leu475.D, Trp582.D, Met583.D, Ala585.D, Leu586.D, Phe588.D, Thr589.D |
| F | -13.6 | Val471.A, Leu475.A, Trp582.A, Met583.A, Ala585.A, Leu586.A, Phe588.A, Thr589.A, Leu619.C, Gly623.C | |
| G | -13.6 | Leu619.A, Gly623.A, Val471.B, Leu475.B, Trp582.B, Met583.B, Ala585.B, Leu586.B, Phe588.B, Thr589.B | |
| H | -13.6 | Val471.C, Leu475.C, Trp582.C, Met583.C, Ala585.C, Leu586.C, Phe588.C, Thr589.C, Leu619.D, Gly623.D | |
| TRPV5 | |||
| TRPV5, closed, bound econazole, Rabbit 6b5v | |||
| 6b5v_EC | E | -13.8 | Val427.C, Thr431.C, Leu435.C, Leu438.C, Met447.C, Glu450.C, Pro453.C, Phe456.C |
| F | -13.8 | Val427.D, Thr431.D, Leu435.D, Leu438.D, Met447.D, Glu450.D, Pro453.D, Phe456.D | |
| G | -13.4 | Val397.C, Leu400.C, Leu401.C, Leu437.C, Met440.C, Val441.C, Arg443.C, Leu444.C | |
| H | -13.7 | Val427.A, Thr431.A, Leu435.A, Leu438.A, Met447.A, Glu450.A, Pro453.A, Phe456.A, Leu460.A | |
| I | -12.8 | Cys556.B, Ile557.B, Ala560.B, Ile564.B, Pro527.D, Thr528.D, Phe531.D, Phe534.D | |
| J | -12.8 | Cys556.A, Ile557.A, Ala560.A, Ile564.A, Pro527.B, Thr528.B, Phe531.B, Phe534.B | |
| K | -13.7 | Val427.B, Thr431.B, Leu435.B, Leu438.B, Met447.B, Glu450.B, Pro453.B, Phe456.B | |
| L | -13.4 | Val397.A, Leu400.A, Leu401.A, Leu437.A, Met440.A, Val441.A, Arg443.A, Leu444.A | |
| 6b5v_IC | E | -14.3 | Leu332.D, Leu335.D, Tyr336.D, Leu338.D, Tyr339.D, Cys342.D, Val391.D, Ile398.D, Ile399.D, Leu402.D, Glu403.D, Met603.D, Met608.D |
| F | -14.2 | Leu332.C, Leu335.C, Tyr336.C, Leu338.C, Tyr339.C, Cys342.C, Val391.C, Ile398.C, Ile399.C, Leu402.C, Met603.C, Lys607.C, Met608.C | |
| G | -14.1 | Ile557.B, Thr558.B, Ala561.B, Ile565.B, Pro424.D, Val427.D, Ile428.D, Phe456.D, Val459.D, Leu460.D, Gln483.D, Ile486.D, Phe487.D | |
| H | -14.1 | Pro424.C, Val427.C, Ile428.C, Phe456.C, Val459.C, Leu460.C, Gln483.C, Ile486.C, Phe487.C, Ile557.D, Thr558.D, Ala561.D, Ile565.D | |
| I | -14.2 | Ile557.A, Thr558.A, Ala561.A, Ile565.A, Pro424.B, Val427.B, Ile428.B, Phe456.B, Val459.B, Leu460.B, Gln483.B, Ile486.B, Phe487.B | |
| J | -14.2 | Leu332.B, Leu335.B, Tyr336.B, Leu338.B, Tyr339.B, Cys342.B, Val391.B, Ile398.B, Ile399.B, Leu402.B, Met603.B, Lys607.B, Met608.B | |
| K | -14.2 | Leu332.A, Leu335.A, Tyr336.A, Leu338.A, Tyr339.A, Cys342.A, Val391.A, Ile398.A, Ile399.A, Leu402.A, Met603.A, Lys607.A, Met608.A | |
| L | -14.1 | Pro424.A, Val427.A, Ile428.A, Phe456.A, Val459.A, Leu460.A, Gln483.A, Ile486.A, Phe487.A, Ile557.C, Thr558.C, Ala561.C, Ile565.C | |
| TRPV5, closed, Rabbit 6dmr | |||
| 6dmr_EC | E | -14.8 | Val499.A, Leu502.A, Tyr526.A, Ile337.B, Ile341.B, Thr344.B, Thr345.B, Ile348.B, Tyr349.B, Trp462.B |
| F | -14.6 | Ile337.A, Ile341.A, Thr344.A, Thr345.A, Ile348.A, Tyr349.A, Trp462.A, Val465.A, Val499.C, Leu502.C, Tyr526.C | |
| G | -14.5 | Ile337.C, Ile341.C, Thr344.C, Thr345.C, Ile348.C, Tyr349.C, Trp462.C, Val465.C, Val499.D, Leu502.D, Tyr526.D | |
| H | -13.5 | Thr431.C, Leu435.C, Leu438.C, Met442.C, Met447.C, Asn448.C, Gly449.C, Val452.C, Pro453.C, Phe456.C | |
| I | -13.4 | Thr431.A, Leu435.A, Leu438.A, Met442.A, Met447.A, Asn448.A, Gly449.A, Val452.A, Pro453.A, Phe456.A | |
| J | -13.2 | Cys556.B, Ile557.B, Ala560.B, Ile564.B, Cys494.D, Met497.D, Pro527.D, Thr528.D, Leu530.D, Phe531.D, Phe534.D | |
| K | -13.2 | Cys494.C, Met497.C, Pro527.C, Thr528.C, Leu530.C, Phe531.C, Phe534.C, Cys556.D, Ile557.D, Ala560.D, Ile564.D | |
| L | -13.1 | Cys494.A, Met497.A, Pro527.A, Leu530.A, Phe531.A, Phe534.A, Cys556.C, Ile557.C, Ala560.C, Ile564.C | |
| M | -14.8 | Val499.B, Leu502.B, Tyr526.B, Ile337.D, Ile341.D, Thr344.D, Thr345.D, Ile348.D, Tyr349.D, Trp462.D | |
| N | -13.7 | Thr431.D, Leu435.D, Leu438.D, Met442.D, Met447.D, Asn448.D, Gly449.D, Val452.D, Pro453.D, Phe456.D | |
| O | -13.5 | Thr431.B, Leu435.B, Leu438.B, Met442.B, Met447.B, Asn448.B, Gly449.B, Val452.B, Pro453.B, Phe456.B | |
| P | -13.1 | Cys556.A, Ile557.A, Ala560.A, Ile564.A, Cys494.B, Met497.B, Pro527.B, Thr528.B, Leu530.B, Phe531.B, Phe534.B | |
| 6dmr_IC | E | -15.6 | Phe425.C, Phe456.C, Val459.C, Leu460.C, Cys463.C, Met466.C, Thr479.C, Ile480.C, Ile482.C, Gln483.C, Ile486.C, Phe504.D, Thr558.D, Ala561.D, Ile565.D |
| F | -15.6 | Phe425.A, Phe456.A, Val459.A, Leu460.A, Cys463.A, Met466.A, Thr479.A, Ile480.A, Ile482.A, Gln483.A, Ile486.A, Phe504.C, Thr558.C, Ala561.C, Ile565.C | |
| G | -13.0 | Phe329.C, Ala333.C, Ile337.C, Val465.C, Phe468.C, Ala469.C, Gly471.C, Phe472.C, Leu475.C, Trp495.D, Ala498.D, Val499.D, Leu530.D | |
| H | -12.9 | Phe329.A, Cys330.A, Ala333.A, Ile337.A, Val465.A, Phe468.A, Ala469.A, Phe472.A, Leu475.A, Trp495.C, Ala498.C, Val499.C, Leu530.C | |
| I | -12.9 | Trp495.A, Ala498.A, Val499.A, Leu530.A, Phe329.B, Ala333.B, Ile337.B, Val465.B, Phe468.B, Ala469.B, Gly471.B, Phe472.B, Leu475.B | |
| J | -15.6 | Phe504.B, Thr558.B, Ala561.B, Ile565.B, Phe425.D, Phe456.D, Val459.D, Leu460.D, Cys463.D, Met466.D, Thr479.D, Ile480.D, Ile482.D, Gln483.D, Ile486.D | |
| K | -15.5 | Phe504.A, Thr558.A, Ala561.A, Ile565.A, Phe425.B, Phe456.B, Val459.B, Leu460.B, Cys463.B, Met466.B, Thr479.B, Ile480.B, Ile482.B, Gln483.B, Ile486.B | |
| L | -12.9 | Trp495.B, Ala498.B, Val499.B, Leu530.B, Phe329.D, Cys330.D, Ala333.D, Ile337.D, Val465.D, Phe468.D, Ala469.D, Phe472.D, Leu475.D | |
| TRPV5, closed, bound PtdIns(4,5)P2, Rabbit 6dmu | |||
| 6dmu_EC | E | -14.2 | Leu502.A, Ile337.B, Ile341.B, Thr344.B, Thr345.B, Ile348.B, Tyr349.B, Trp462.B |
| F | -14.2 | Ile337.A, Ile341.A, Thr344.A, Thr345.A, Ile348.A, Tyr349.A, Trp462.A, Leu502.C | |
| G | -14.1 | Leu502.B, Tyr526.B, Ile337.D, Ile341.D, Thr344.D, Thr345.D, Ile348.D, Tyr349.D, Trp462.D | |
| H | -13.3 | Cys494.C, Ala498.C, Ile501.C, Pro527.C, Leu530.C, Phe531.C, Phe534.C, Phe553.D, Cys556.D, Ile557.D | |
| I | -13.2 | Cys494.A, Pro527.A, Phe531.A, Phe553.C, Cys556.C, Ile557.C, Ala560.C, Ile564.C | |
| J | -13.2 | Phe553.A, Cys556.A, Ile557.A, Ala560.A, Ile564.A, Cys494.B, Pro527.B, Phe531.B | |
| K | -13.0 | Leu335.A, Leu338.A, Cys342.A, Thr345.A, Tyr349.A, Gln381.A, Ile384.A, Arg385.A, Val391.A | |
| L | -13.0 | Leu335.B, Leu338.B, Cys342.B, Thr345.B, Tyr349.B, Gln381.B, Ile384.B, Arg385.B, Val391.B | |
| M | -14.1 | Ile337.C, Ile341.C, Thr344.C, Thr345.C, Ile348.C, Tyr349.C, Trp462.C, Leu502.D, Tyr526.D | |
| N | -13.2 | Phe553.B, Cys556.B, Ile557.B, Cys494.D, Ala498.D, Ile501.D, Pro527.D, Leu530.D, Phe531.D, Phe534.D | |
| O | -13.0 | Leu335.C, Leu338.C, Cys342.C, Thr345.C, Tyr349.C, Gln381.C, Ile384.C, Arg385.C, Val391.C | |
| P | -13.0 | Leu335.D, Leu338.D, Cys342.D, Thr345.D, Tyr349.D, Gln381.D, Ile384.D, Arg385.D, Val391.D | |
| 6dmu_IC | E | -16.6 | Ile337.A, Ile341.A, Trp462.A, Val465.A, Phe468.A, Ala469.A, Phe472.A, Leu475.A, Trp495.C, Leu496.C, Ala498.C, Val499.C, Leu502.C |
| F | -16.5 | Trp495.B, Leu496.B, Ala498.B, Val499.B, Leu502.B, Ile337.D, Ile341.D, Trp462.D, Val465.D, Phe468.D, Ala469.D, Phe472.D, Leu475.D | |
| G | -16.3 | Trp495.A, Leu496.A, Ala498.A, Val499.A, Leu502.A, Ile337.B, Ile341.B, Trp462.B, Val465.B, Phe468.B, Ala469.B, Phe472.B, Leu475.B | |
| H | -14.5 | Ile557.A, Thr558.A, Ala561.A, Ile565.A, Phe425.B, Ile428.B, Phe456.B, Val459.B, Leu460.B, Cys463.B, Met466.B, Thr479.B, Ile480.B, Ile482.B, Gln483.B, Ile486.B, Phe487.B | |
| I | -14.1 | Thr539.A, Asn572.A, Thr539.B, Ile540.B, Ile575.B, Thr539.C, Ile575.C, Thr539.D, Asn572.D, Ile575.D | |
| J | -13.9 | Leu332.A, Leu335.A, Tyr336.A, Leu338.A, Tyr339.A, Cys342.A, Val391.A, Gly395.A, Ile398.A, Ile399.A, Leu402.A, Lys607.A | |
| K | -13.8 | Leu332.B, Leu335.B, Tyr336.B, Leu338.B, Tyr339.B, Cys342.B, Val391.B, Gly395.B, Ile398.B, Ile399.B, Leu402.B, Lys607.B | |
| L | -13.1 | Phe425.A, Ile428.A, Phe456.A, Val459.A, Leu460.A, Cys463.A, Met466.A, Thr479.A, Ile482.A, Gln483.A, Ile486.A, Phe487.A, Ile557.C, Thr558.C, Ala561.C, Ile565.C | |
| M | -12.4 | Pro424.B, Val427.B, Ile428.B, Thr431.B, Leu435.B, Phe456.B, Leu460.B, Phe487.B | |
| N | -12.4 | Phe416.A, Pro424.A, Val427.A, Ile428.A, Thr431.A, Leu435.A, Phe456.A, Phe487.A | |
| O | -16.3 | Ile337.C, Ile341.C, Trp462.C, Val465.C, Phe468.C, Ala469.C, Phe472.C, Leu475.C, Trp495.D, Leu496.D, Ala498.D, Val499.D, Leu502.D | |
| P | -14.5 | Ile557.B, Thr558.B, Ala561.B, Ile565.B, Phe425.D, Ile428.D, Phe456.D, Val459.D, Leu460.D, Cys463.D, Met466.D, Thr479.D, Ile482.D, Gln483.D, Ile486.D, Phe487.D | |
| Q | -14.5 | Phe425.C, Ile428.C, Phe456.C, Val459.C, Leu460.C, Cys463.C, Met466.C, Thr479.C, Ile482.C, Gln483.C, Ile486.C, Phe487.C, Ile557.D, Thr558.D, Ala561.D, Ile565.D | |
| R | -13.9 | Leu332.D, Leu335.D, Tyr336.D, Leu338.D, Tyr339.D, Cys342.D, Val391.D, Gly395.D, Ile398.D, Ile399.D, Leu402.D, Lys607.D | |
| S | -13.8 | Leu332.C, Leu335.C, Tyr336.C, Leu338.C, Tyr339.C, Cys342.C, Val391.C, Gly395.C, Ile398.C, Ile399.C, Leu402.C, Lys607.C | |
| T | -12.4 | Pro424.C, Val427.C, Ile428.C, Thr431.C, Leu435.C, Phe456.C, Leu460.C, Phe487.C | |
| TRPV5, Rabbit 6o1n | |||
| 6o1n_EC | E | -14.2 | Ile341.A, Thr345.A, Ile348.A, Tyr349.A, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B |
| F | -14.3 | Ile341.C, Thr345.C, Ile348.C, Tyr349.C, Trp462.C, Val499.D, Leu502.D, Tyr526.D | |
| G | -14.1 | Ile341.B, Thr345.B, Ile348.B, Tyr349.B, Trp462.B, Val499.C, Leu502.C, Tyr526.C | |
| H | -13.9 | Trp495.A, Ala498.A, Val499.A, Leu502.A, Tyr526.A, Pro527.A, Leu530.A, Ile341.D, Thr345.D, Ile348.D, Tyr349.D | |
| 6o1n_IC | E | -13.9 | Phe416.B, Pro424.B, Val427.B, Ile428.B, Phe456.B, Val459.B, Leu460.B, Phe487.B, Ile557.C, Thr558.C, Ala561.C |
| F | -13.5 | Phe416.A, Gly417.A, Pro424.A, Val427.A, Ile428.A, Phe456.A, Val459.A, Leu460.A, Phe487.A, Ile557.B, Thr558.B, Ala561.B | |
| G | -13.1 | Ala412.A, Ser413.A, Phe416.A, Val427.A, Thr431.A, Leu435.A, Leu438.A, Phe456.A | |
| H | -13.0 | Ala412.B, Ser413.B, Phe416.B, Val427.B, Thr431.B, Leu435.B, Leu438.B, Phe456.B | |
| I | -14.4 | Pro424.C, Phe425.C, Ile428.C, Phe456.C, Leu460.C, Met466.C, Thr479.C, Ile480.C, Ile482.C, Gln483.C, Ile486.C, Phe487.C, Ile557.D, Thr558.D, Ala561.D, Ile565.D | |
| J | -13.8 | Phe416.C, Gly417.C, Pro424.C, Val427.C, Ile428.C, Phe456.C, Val459.C, Leu460.C, Phe487.C, Ile557.D, Thr558.D, Ala561.D | |
| TRPV5, Rabbit 6o1p | |||
| 6o1p_EC | E | -14.7 | Ile341.C, Thr344.C, Thr345.C, Ile348.C, Tyr349.C, Trp495.D, Ala498.D, Leu502.D, Tyr526.D, Pro527.D, Leu530.D |
| F | -14.4 | Ile341.A, Thr345.A, Ile348.A, Tyr349.A, Trp495.B, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B | |
| G | -14.4 | Ile341.B, Thr345.B, Ile348.B, Tyr349.B, Trp495.C, Ala498.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C | |
| H | -14.6 | Trp495.A, Ala498.A, Leu502.A, Tyr526.A, Pro527.A, Leu530.A, Ile341.D, Thr345.D, Ile348.D, Tyr349.D | |
| 6o1p_IC | [none] | ||
| TRPV5, Rabbit 6o1u | |||
| 6o1u_EC | E | -14.6 | Phe553.A, Cys556.A, Ala560.A, Ile564.A, Cys494.B, Met497.B, Ala498.B, Ile501.B, Pro527.B, Thr528.B, Leu530.B, Phe531.B, Phe534.B |
| F | -14.7 | Leu551.C, Phe553.C, Cys556.C, Ile557.C, Cys494.D, Ala498.D, Ile501.D, Pro527.D, Thr528.D, Leu530.D, Phe531.D, Phe534.D | |
| G | -14.7 | Phe553.B, Cys556.B, Ile557.B, Ala560.B, Leu490.C, Cys494.C, Ala498.C, Ile501.C, Pro527.C, Thr528.C, Leu530.C, Phe531.C, Phe534.C | |
| H | -14.7 | Cys494.A, Ala498.A, Ile501.A, Pro527.A, Thr528.A, Leu530.A, Phe531.A, Phe534.A, Phe553.D, Cys556.D, Ile557.D | |
| I | -14.4 | Trp495.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C, Ile337.D, Ile341.D, Thr345.D, Ile348.D, Tyr349.D, Trp462.D | |
| J | -14.2 | Trp495.A, Leu502.A, Tyr526.A, Pro527.A, Leu530.A, Ile337.B, Ile341.B, Thr344.B, Thr345.B, Ile348.B, Tyr349.B, Trp462.B | |
| K | -14.1 | Ile337.A, Ile341.A, Thr345.A, Ile348.A, Tyr349.A, Trp462.A, Trp495.D, Leu502.D, Tyr526.D, Pro527.D, Leu530.D | |
| L | -13.3 | Tyr377.D, Leu386.D, Leu390.D, Val393.D, Thr394.D, Val397.D, Leu401.D, Met440.D, Leu444.D | |
| M | -13.2 | Tyr377.A, Leu386.A, Leu390.A, Val393.A, Thr394.A, Val397.A, Leu401.A, Met440.A, Leu444.A | |
| N | -14.4 | Trp495.B, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B, Thr345.C, Ile348.C, Tyr349.C | |
| O | -13.1 | Tyr377.B, Leu386.B, Leu390.B, Val393.B, Thr394.B, Val397.B, Leu401.B, Met440.B, Leu444.B | |
| 6o1u_IC | E | -15.3 | Thr539.A, Asp542.A, Asn572.A, Ile575.A, Thr539.B, Ile575.B, Thr539.C, Asn572.C, Ile575.C, Thr539.D, Asn572.D, Ile575.D |
| F | -14.1 | Trp495.A, Leu496.A, Val499.A, Leu502.A, Ile337.B, Ile341.B, Trp462.B, Val465.B, Met466.B, Phe468.B, Ala469.B, Gly471.B, Phe472.B, Leu475.B | |
| G | -14.0 | Ile337.A, Ile341.A, Trp462.A, Val465.A, Met466.A, Phe468.A, Ala469.A, Arg470.A, Phe472.A, Leu475.A, Trp495.D, Leu496.D, Val499.D, Leu502.D | |
| H | -14.0 | Trp495.C, Leu496.C, Val499.C, Leu502.C, Ile337.D, Ile341.D, Trp462.D, Val465.D, Met466.D, Phe468.D, Ala469.D, Phe472.D, Leu475.D | |
| I | -13.0 | Leu332.D, Leu335.D, Tyr336.D, Leu338.D, Tyr339.D, Val391.D, Ile398.D, Leu402.D, Lys607.D, Met608.D | |
| J | -13.0 | Leu332.A, Leu335.A, Tyr336.A, Leu338.A, Tyr339.A, Val391.A, Ile398.A, Leu402.A, Leu604.A, Lys607.A, Met608.A | |
| K | -12.9 | Phe504.C, Met554.C, Ile557.C, Thr558.C, Ala561.C, Phe416.D, Pro424.D, Val427.D, Ile428.D, Phe456.D, Val459.D, Leu460.D, Phe487.D | |
| L | -12.0 | Phe416.A, Gly417.A, Pro424.A, Val427.A, Ile428.A, Thr431.A, Leu435.A, Val452.A, Pro453.A, Phe456.A, Leu460.A, Phe487.A | |
| M | -12.0 | Pro424.C, Val427.C, Ile428.C, Thr431.C, Leu435.C, Val452.C, Pro453.C, Phe456.C, Leu460.C, Phe487.C | |
| N | -13.8 | Trp495.B, Leu496.B, Val499.B, Leu502.B, Ile337.C, Ile341.C, Trp462.C, Val465.C, Met466.C, Phe468.C, Ala469.C, Phe472.C, Leu475.C | |
| O | -13.1 | Leu332.C, Leu335.C, Leu338.C, Tyr339.C, Cys342.C, Val391.C, Ile398.C, Leu402.C, Met608.C, Pro609.C | |
| P | -12.8 | Leu332.B, Leu335.B, Leu338.B, Tyr339.B, Cys342.B, Val391.B, Ile398.B, Leu402.B, Met608.B | |
| Q | -12.7 | Phe504.A, Met554.A, Ile557.A, Thr558.A, Ala561.A, Phe416.B, Gly417.B, Pro424.B, Val427.B, Ile428.B, Phe456.B, Val459.B, Leu460.B, Phe487.B | |
| TRPV5, calmodulin bound, Rabbit 6o20 | |||
| 6o20_EC | E | -14.5 | Ile337.A, Ile341.A, Thr345.A, Ile348.A, Tyr349.A, Trp462.A, Trp495.B, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B |
| F | -14.3 | Ile337.B, Ile341.B, Thr345.B, Ile348.B, Tyr349.B, Trp462.B, Trp495.C, Ala498.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C | |
| G | -14.2 | Ile337.C, Ile341.C, Thr345.C, Ile348.C, Tyr349.C, Trp462.C, Trp495.D, Ala498.D, Leu502.D, Tyr526.D, Pro527.D, Leu530.D | |
| H | -13.0 | Leu335.B, Leu338.B, Cys342.B, Thr345.B, Tyr349.B, Gln381.B, Ile384.B, Arg385.B, Val391.B | |
| I | -13.0 | Leu335.C, Leu338.C, Ile341.C, Cys342.C, Thr345.C, Tyr349.C, Ile384.C, Val391.C | |
| J | -12.4 | Leu386.B, Leu390.B, Val393.B, Thr394.B, Val397.B, Ile398.B, Leu401.B, Leu444.B | |
| K | -12.4 | Leu386.C, Leu390.C, Val393.C, Thr394.C, Val397.C, Ile398.C, Leu401.C, Leu444.C | |
| L | -14.5 | Trp495.A, Ala498.A, Leu502.A, Tyr526.A, Pro527.A, Leu530.A, Ile337.D, Ile341.D, Thr345.D, Ile348.D, Tyr349.D | |
| M | -13.1 | Leu335.A, Leu338.A, Ile341.A, Cys342.A, Thr345.A, Tyr349.A, Ile384.A, Arg385.A, Val391.A | |
| N | -13.0 | Leu335.D, Leu338.D, Cys342.D, Thr345.D, Tyr349.D, Gln381.D, Ile384.D, Arg385.D, Val391.D | |
| O | -12.4 | Leu386.D, Leu390.D, Val393.D, Thr394.D, Val397.D, Ile398.D, Leu401.D, Leu444.D | |
| 6o20_IC | E | -14.0 | Phe416.B, Gly417.B, Pro424.B, Val427.B, Ile428.B, Phe456.B, Val459.B, Leu460.B, Phe487.B, Phe504.C, Ile557.C, Thr558.C, Ala561.C |
| F | -14.0 | Phe416.C, Gly417.C, Pro424.C, Val427.C, Ile428.C, Phe456.C, Val459.C, Leu460.C, Phe487.C, Phe504.D, Ile557.D, Thr558.D, Ala561.D | |
| G | -14.0 | Phe416.A, Gly417.A, Pro424.A, Val427.A, Ile428.A, Phe456.A, Val459.A, Leu460.A, Phe487.A, Phe504.B, Ile557.B, Thr558.B, Ala561.B | |
| H | -13.9 | Phe504.A, Ile557.A, Thr558.A, Ala561.A, Phe416.D, Gly417.D, Pro424.D, Val427.D, Ile428.D, Phe456.D, Val459.D, Leu460.D, Phe487.D | |
| TRPV6 | |||
| TRPV6, closed, [Incomplete helices and loops], Rat 5iwk | |||
| 5iwk_EC | E | -14.2 | Ile340.D, Met344.D, Val347.D, Tyr348.D, Trp461.D, Trp494.D, Leu501.D, Tyr525.D, Pro526.D, Leu529.D |
| F | -14.1 | Ile340.B, Met344.B, Val347.B, Tyr348.B, Trp461.B, Trp494.B, Leu501.B, Tyr525.B, Pro526.B, Leu529.B | |
| G | -13.3 | Met496.B, Pro526.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D, Ala559.D, Ile563.D | |
| H | -13.3 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Met496.D, Pro526.D, Phe530.D | |
| I | -12.4 | Thr430.D, Phe433.D, Met434.D, Val437.D, Met441.D, Val451.D, Pro452.D, Phe455.D, Phe552.D | |
| J | -12.4 | Thr430.A, Phe433.A, Met434.A, Val437.A, Met441.A, Val451.A, Pro452.A, Phe455.A, Phe552.A | |
| K | -14.1 | Ile340.A, Met344.A, Val347.A, Tyr348.A, Trp461.A, Trp494.A, Leu501.A, Tyr525.A, Pro526.A, Leu529.A | |
| L | -14.1 | Ile340.C, Met344.C, Val347.C, Tyr348.C, Trp461.C, Trp494.C, Leu501.C, Tyr525.C, Pro526.C, Leu529.C | |
| M | -13.3 | Phe552.B, Ser555.B, Ile556.B, Ala559.B, Ile563.B, Cys493.C, Met496.C, Ala497.C, Pro526.C, Leu529.C, Phe530.C | |
| N | -13.3 | Cys493.A, Met496.A, Ala497.A, Pro526.A, Leu529.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C | |
| O | -12.4 | Thr430.C, Phe433.C, Met434.C, Val437.C, Met441.C, Val451.C, Pro452.C, Phe455.C, Phe552.C | |
| P | -12.4 | Thr430.B, Phe433.B, Met434.B, Val437.B, Met441.B, Val451.B, Pro452.B, Phe455.B, Phe552.B | |
| 5iwk_IC | [none] | ||
| TRPV6, closed, Ca bound, [Incomplete helices and loops], Rat 5iwp | |||
| 5iwp_EC | E | -13.8 | Ile340.D, Met344.D, Val347.D, Tyr348.D, Leu501.D, Tyr525.D, Pro526.D, Leu529.D |
| F | -13.8 | Ile340.B, Met344.B, Val347.B, Tyr348.B, Leu501.B, Tyr525.B, Pro526.B, Leu529.B | |
| G | -13.3 | Ile334.B, Leu337.B, Cys341.B, Met344.B, Tyr348.B, Leu383.B, Arg384.B, Gly387.B, Val390.B | |
| H | -13.3 | Ile334.D, Leu337.D, Cys341.D, Met344.D, Tyr348.D, Lys380.D, Leu383.D, Arg384.D, Gly387.D, Val390.D | |
| I | -13.1 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Met496.D, Pro526.D, Phe530.D | |
| J | -13.1 | Met496.B, Pro526.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D, Ala559.D, Ile563.D | |
| K | -13.8 | Ile340.A, Met344.A, Val347.A, Tyr348.A, Leu501.A, Tyr525.A, Pro526.A, Leu529.A | |
| L | -13.7 | Ile340.C, Met344.C, Val347.C, Tyr348.C, Leu501.C, Tyr525.C, Pro526.C, Leu529.C | |
| M | -13.3 | Ile334.C, Leu337.C, Cys341.C, Met344.C, Tyr348.C, Lys380.C, Leu383.C, Arg384.C, Gly387.C, Val390.C | |
| N | -13.3 | Ile334.A, Leu337.A, Cys341.A, Met344.A, Tyr348.A, Leu383.A, Arg384.A, Gly387.A, Val390.A | |
| O | -13.1 | Phe552.B, Ser555.B, Ile556.B, Ala559.B, Ile563.B, Met496.C, Pro526.C, Phe530.C | |
| P | -13.1 | Met496.A, Pro526.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C | |
| 5iwp_IC | E | -13.4 | Ile334.B, Leu337.B, Tyr338.B, Cys341.B, Val390.B, Ile397.B, Val401.B, Lys606.B, Leu607.B, Pro608.B |
| F | -13.4 | Ile334.D, Leu337.D, Tyr338.D, Cys341.D, Val390.D, Ile397.D, Val401.D, Lys606.D, Leu607.D, Pro608.D | |
| G | -13.4 | Ile334.A, Leu337.A, Tyr338.A, Cys341.A, Val390.A, Ile397.A, Val401.A, Lys606.A, Leu607.A, Pro608.A | |
| H | -13.4 | Ile334.C, Leu337.C, Tyr338.C, Cys341.C, Val390.C, Ile397.C, Val401.C, Lys606.C, Leu607.C, Pro608.C | |
| TRPV6, closed, Ba bound, [Incomplete helices and loops], Rat 5iwr | |||
| 5iwr_EC | E | -13.8 | Ile340.B, Met344.B, Val347.B, Tyr348.B, Leu501.B, Tyr525.B, Pro526.B, Leu529.B |
| F | -13.8 | Ile340.C, Met344.C, Val347.C, Tyr348.C, Leu501.C, Tyr525.C, Pro526.C, Leu529.C | |
| G | -13.3 | Met496.B, Ala497.B, Ile500.B, Pro526.B, Leu529.B, Phe530.B, Phe533.B, Phe552.D, Ser555.D, Ile556.D, Ala559.D, Ile563.D | |
| H | -13.3 | Ile334.B, Leu337.B, Cys341.B, Met344.B, Tyr348.B, Leu383.B, Arg384.B, Gly387.B, Val390.B | |
| I | -13.3 | Phe552.B, Ser555.B, Ile556.B, Ala559.B, Ile563.B, Met496.C, Ala497.C, Ile500.C, Pro526.C, Leu529.C, Phe530.C, Phe533.C | |
| J | -13.3 | Ile334.C, Leu337.C, Cys341.C, Met344.C, Tyr348.C, Leu383.C, Arg384.C, Gly387.C, Val390.C | |
| K | -12.9 | Phe433.B, Met434.B, Val437.B, Met441.B, Ser446.B, Gly448.B, Val451.B, Pro452.B, Phe455.B | |
| L | -12.9 | Phe433.D, Met434.D, Val437.D, Met441.D, Ser446.D, Gly448.D, Val451.D, Pro452.D, Phe455.D | |
| M | -13.3 | Ile334.D, Leu337.D, Cys341.D, Met344.D, Tyr348.D, Leu383.D, Arg384.D, Gly387.D, Val390.D | |
| N | -13.8 | Ile340.D, Met344.D, Val347.D, Tyr348.D, Leu501.D, Tyr525.D, Pro526.D, Leu529.D | |
| O | -13.8 | Ile340.A, Met344.A, Val347.A, Tyr348.A, Leu501.A, Tyr525.A, Pro526.A, Leu529.A | |
| P | -13.3 | Met496.A, Ala497.A, Ile500.A, Pro526.A, Leu529.A, Phe530.A, Phe533.A, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C | |
| Q | -13.3 | Ile334.A, Leu337.A, Cys341.A, Met344.A, Tyr348.A, Leu383.A, Arg384.A, Gly387.A, Val390.A | |
| R | -13.3 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Met496.D, Ala497.D, Ile500.D, Pro526.D, Leu529.D, Phe530.D, Phe533.D | |
| S | -13.0 | Phe433.A, Met434.A, Val437.A, Met441.A, Ser446.A, Gly448.A, Val451.A, Pro452.A, Phe455.A | |
| T | -13.0 | Phe433.C, Met434.C, Val437.C, Met441.C, Ser446.C, Gly448.C, Val451.C, Pro452.C, Phe455.C | |
| 5iwr_IC | E | -13.6 | Ile334.B, Leu337.B, Tyr338.B, Cys341.B, Val390.B, Ile397.B, Val401.B, Lys606.B, Leu607.B, Pro608.B |
| F | -13.6 | Ile334.D, Leu337.D, Tyr338.D, Cys341.D, Val390.D, Ile397.D, Val401.D, Lys606.D, Leu607.D, Pro608.D | |
| G | -13.5 | Ile334.C, Leu337.C, Tyr338.C, Cys341.C, Val390.C, Ile397.C, Val401.C, Lys606.C, Leu607.C, Pro608.C | |
| H | -13.5 | Ile334.A, Leu337.A, Tyr338.A, Cys341.A, Val390.A, Ile397.A, Val401.A, Lys606.A, Leu607.A, Pro608.A | |
| TRPV6, closed, Gd bound, [Incomplete helices and loops], Rat 5iwt | |||
| 5iwt_EC | E | -13.7 | Ile340.D, Met344.D, Val347.D, Tyr348.D, Ala497.D, Leu501.D, Tyr525.D, Leu529.D |
| F | -13.7 | Ile340.A, Met344.A, Val347.A, Tyr348.A, Ala497.A, Leu501.A, Tyr525.A, Leu529.A | |
| G | -13.6 | Ile334.D, Leu337.D, Cys341.D, Met344.D, Tyr348.D, Lys380.D, Leu383.D, Arg384.D, Gly387.D, Val390.D | |
| H | -13.5 | Ile334.C, Leu337.C, Cys341.C, Met344.C, Tyr348.C, Lys380.C, Leu383.C, Arg384.C, Gly387.C, Val390.C | |
| I | -13.5 | Ile334.A, Leu337.A, Cys341.A, Met344.A, Tyr348.A, Lys380.A, Leu383.A, Arg384.A, Gly387.A, Val390.A | |
| J | -13.2 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Met496.D, Ala497.D, Pro526.D, Leu529.D | |
| K | -13.2 | Met496.A, Ala497.A, Pro526.A, Leu529.A, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C | |
| L | -12.6 | Thr430.A, Phe433.A, Met434.A, Val437.A, Met441.A, Gly448.A, Val451.A, Pro452.A, Phe552.A | |
| M | -12.6 | Thr430.C, Phe433.C, Met434.C, Val437.C, Met441.C, Gly448.C, Val451.C, Pro452.C | |
| N | -13.7 | Ile340.C, Met344.C, Val347.C, Tyr348.C, Ala497.C, Leu501.C, Tyr525.C, Leu529.C | |
| O | -13.7 | Ile340.B, Met344.B, Val347.B, Tyr348.B, Ala497.B, Leu501.B, Tyr525.B, Leu529.B | |
| P | -13.5 | Ile334.B, Leu337.B, Cys341.B, Met344.B, Tyr348.B, Lys380.B, Leu383.B, Arg384.B, Gly387.B, Val390.B | |
| Q | -13.2 | Met496.B, Ala497.B, Pro526.B, Leu529.B, Phe552.D, Ser555.D, Ile556.D, Ala559.D, Ile563.D | |
| R | -13.2 | Phe552.B, Ser555.B, Ile556.B, Ala559.B, Ile563.B, Met496.C, Ala497.C, Pro526.C, Leu529.C | |
| S | -12.6 | Thr430.B, Phe433.B, Met434.B, Val437.B, Met441.B, Gly448.B, Val451.B, Pro452.B, Phe552.B | |
| T | -12.6 | Thr430.D, Phe433.D, Met434.D, Val437.D, Met441.D, Gly448.D, Val451.D, Pro452.D | |
| 5iwt_IC | E | -13.5 | Leu331.C, Ile334.C, Tyr335.C, Leu337.C, Tyr338.C, Cys341.C, Val390.C, Gly394.C, Ile397.C, Ile398.C, Val401.C, Glu402.C, Phe424.C, Met602.C, Leu603.C, Lys606.C |
| F | -13.5 | Leu331.D, Ile334.D, Tyr335.D, Leu337.D, Tyr338.D, Cys341.D, Val390.D, Gly394.D, Ile397.D, Ile398.D, Val401.D, Glu402.D, Phe424.D, Lys606.D | |
| G | -13.5 | Leu331.B, Ile334.B, Tyr335.B, Leu337.B, Tyr338.B, Cys341.B, Val390.B, Gly394.B, Ile397.B, Ile398.B, Val401.B, Glu402.B, Phe424.B, Met602.B, Leu603.B, Lys606.B | |
| TRPV6, [Incomplete helices and loops], Human 6bo8 | |||
| 6bo8_EC | E | -15.5 | Leu490.A, Cys494.A, Met497.A, Ala498.A, Ile501.A, Pro527.A, Met528.A, Leu530.A, Phe531.A, Phe534.A, Phe553.B, Ser556.B, Ile557.B, Ala560.B, Ile564.B |
| F | -14.7 | Cys494.C, Pro527.C, Met528.C, Phe531.C, Phe553.D, Ser556.D, Ile557.D, Ala560.D, Ile564.D | |
| G | -14.5 | Cys494.B, Tyr524.B, Pro527.B, Met528.B, Phe531.B, Phe553.C, Ser556.C, Ile557.C, Ile564.C | |
| H | -14.1 | Ile341.A, Met345.A, Ile348.A, Tyr349.A, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B | |
| I | -14.0 | Ala498.A, Leu502.A, Tyr526.A, Leu530.A, Ile341.D, Met345.D, Ile348.D, Tyr349.D, Trp462.D | |
| J | -13.7 | Ile341.B, Ile348.B, Tyr349.B, Trp462.B, Ala498.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C | |
| K | -15.1 | Phe553.A, Ser556.A, Ile557.A, Ala560.A, Ile564.A, Cys494.D, Met497.D, Ala498.D, Ile501.D, Pro527.D, Met528.D, Leu530.D, Phe531.D, Phe534.D | |
| L | -13.6 | Ile341.C, Met345.C, Ile348.C, Tyr349.C, Trp462.C, Trp495.D, Leu502.D, Tyr526.D | |
| 6bo8_IC | E | -17.0 | Pro424.A, Phe425.A, Leu428.A, Phe456.A, Val459.A, Leu460.A, Cys463.A, Thr479.A, Ile482.A, Gln483.A, Ile486.A, Phe487.A, Met554.B, Ile557.B, Thr558.B, Ala561.B, Ile565.B |
| F | -16.6 | Pro424.B, Phe425.B, Leu428.B, Phe456.B, Val459.B, Leu460.B, Cys463.B, Met466.B, Thr479.B, Ile482.B, Gln483.B, Ile486.B, Phe487.B, Met554.C, Ile557.C, Thr558.C, Ala561.C, Ile565.C | |
| G | -15.3 | Thr539.A, Ile575.A, Thr539.B, Ile575.B, Thr539.C, Asn572.C, Ile575.C, Thr539.D, Asn572.D, Ile575.D | |
| H | -16.8 | Met554.A, Ile557.A, Thr558.A, Ala561.A, Ile565.A, Pro424.D, Phe425.D, Leu428.D, Phe456.D, Val459.D, Leu460.D, Cys463.D, Met466.D, Thr479.D, Ile482.D, Gln483.D, Ile486.D, Phe487.D | |
| I | -15.5 | Pro424.C, Phe425.C, Leu428.C, Phe456.C, Val459.C, Leu460.C, Cys463.C, Thr479.C, Ile482.C, Gln483.C, Ile486.C, Phe487.C, Met554.D, Ile557.D, Thr558.D, Ala561.D, Ile565.D | |
| TRPV6, [Incomplete helices and loops], Human 6bo9 | |||
| 6bo9_EC | E | -14.0 | Cys494.B, Met497.B, Ile501.B, Pro527.B, Met528.B, Phe531.B, Phe534.B, Phe553.C, Ser556.C, Ile557.C, Ile564.C |
| F | -14.0 | Cys494.A, Met497.A, Ile501.A, Pro527.A, Met528.A, Phe531.A, Phe534.A, Phe553.B, Ser556.B, Ile557.B, Ile564.B | |
| G | -13.8 | Thr539.A, Ile540.A, Asp542.A, Ile575.A, Thr539.B, Ile540.B, Ile541.B, Asp542.B, Thr539.C, Ile540.C, Asp542.C, Thr539.D, Asp542.D, Ile575.D | |
| H | -13.8 | Ile341.B, Met345.B, Ile348.B, Tyr349.B, Ala498.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C | |
| I | -13.7 | Ile341.A, Ile348.A, Tyr349.A, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B | |
| J | -13.7 | Ala498.A, Leu502.A, Tyr526.A, Pro527.A, Leu530.A, Ile341.D, Met345.D, Ile348.D, Tyr349.D | |
| K | -13.4 | Cys494.C, Met497.C, Ala498.C, Ile501.C, Pro527.C, Met528.C, Leu530.C, Phe531.C, Phe534.C, Phe553.D, Ser556.D | |
| L | -14.1 | Phe553.A, Ser556.A, Ile557.A, Ile564.A, Cys494.D, Met497.D, Ile501.D, Pro527.D, Met528.D, Phe531.D, Phe534.D | |
| M | -13.8 | Ile341.B, Met345.B, Ile348.B, Tyr349.B, Ala498.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C | |
| N | -13.7 | Ile341.C, Ile348.C, Tyr349.C, Ala498.D, Leu502.D, Tyr526.D, Pro527.D, Leu530.D | |
| 6bo9_IC | [none] | ||
| TRPV6, [Incomplete helices and loops], Human 6bob | |||
| 6bob_EC | [none] | ||
| 6bob_IC | [none] | ||
| TRPV6, plus 2-APB, Rat 6d7o | |||
| 6d7o_EC | E | -13.6 | Ile334.B, Leu337.B, Cys341.B, Met344.B, Tyr348.B, Lys380.B, Leu383.B, Arg384.B, Gly387.B, Val390.B |
| F | -13.6 | Ile334.C, Leu337.C, Cys341.C, Met344.C, Tyr348.C, Lys380.C, Leu383.C, Arg384.C, Gly387.C, Val390.C | |
| G | -13.6 | Phe552.B, Ser555.B, Ile556.B, Cys493.C, Met496.C, Ala497.C, Ile500.C, Pro526.C, Leu529.C, Phe530.C, Phe533.C | |
| H | -13.6 | Cys493.B, Met496.B, Ala497.B, Ile500.B, Pro526.B, Leu529.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D | |
| I | -13.5 | Phe552.A, Ser555.A, Ile556.A, Cys493.D, Met496.D, Ala497.D, Ile500.D, Pro526.D, Leu529.D, Phe530.D | |
| J | -13.3 | Ile340.A, Tyr348.A, Trp461.A, Trp494.C, Val498.C, Leu501.C, Tyr525.C, Leu529.C | |
| K | -13.3 | Trp494.B, Val498.B, Leu501.B, Tyr525.B, Leu529.B, Ile340.C, Tyr348.C, Trp461.C | |
| L | -13.3 | Ile340.B, Tyr348.B, Trp461.B, Trp494.D, Val498.D, Leu501.D, Tyr525.D, Leu529.D | |
| M | -13.1 | Pro526.B, Met527.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D, Ala559.D, Ile563.D | |
| N | -13.1 | Ile334.A, Leu337.A, Cys341.A, Met344.A, Tyr348.A, Leu383.A, Arg384.A, Gly387.A, Val390.A | |
| O | -13.1 | Phe552.B, Ser555.B, Ile556.B, Ala559.B, Asp524.C, Pro526.C, Met527.C, Phe530.C | |
| P | -13.6 | Ile334.D, Leu337.D, Cys341.D, Met344.D, Tyr348.D, Leu383.D, Arg384.D, Gly387.D, Val390.D | |
| Q | -13.5 | Cys493.A, Met496.A, Ala497.A, Ile500.A, Pro526.A, Leu529.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C | |
| R | -13.3 | Trp494.A, Val498.A, Leu501.A, Tyr525.A, Leu529.A, Ile340.D, Tyr348.D, Trp461.D | |
| S | -13.1 | Asp524.A, Pro526.A, Met527.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C | |
| T | -13.1 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Asp524.D, Pro526.D, Met527.D, Phe530.D | |
| 6d7o_IC | E | -15.5 | Trp494.B, Val498.B, Leu501.B, Phe328.C, Ala333.C, Val336.C, Ile340.C, Trp461.C, Val464.C, Phe467.C, Ala468.C, Phe471.C |
| F | -15.5 | Phe328.B, Ala333.B, Val336.B, Ile340.B, Trp461.B, Val464.B, Phe467.B, Ala468.B, Phe471.B, Trp494.D, Val498.D, Leu501.D | |
| G | -15.5 | Phe328.A, Ala333.A, Val336.A, Ile340.A, Trp461.A, Val464.A, Phe467.A, Ala468.A, Phe471.A, Trp494.C, Val498.C, Leu501.C | |
| H | -13.1 | Leu331.B, Ile334.B, Tyr338.B, Cys341.B, Val390.B, Ile397.B, Val401.B, Lys606.B | |
| I | -13.1 | Leu331.C, Ile334.C, Tyr338.C, Cys341.C, Val390.C, Ile397.C, Val401.C, Lys606.C, Leu607.C | |
| J | -15.5 | Trp494.A, Val498.A, Leu501.A, Phe328.D, Ala333.D, Val336.D, Ile340.D, Trp461.D, Val464.D, Phe467.D, Ala468.D, Phe471.D | |
| K | -13.1 | Leu331.D, Ile334.D, Tyr338.D, Cys341.D, Val390.D, Ile397.D, Val401.D, Lys606.D | |
| L | -13.1 | Leu331.A, Ile334.A, Tyr338.A, Cys341.A, Val390.A, Ile397.A, Val401.A, Lys606.A | |
| TRPV6, Rat 6d7p | |||
| 6d7p_EC | E | -13.6 | Ile334.A, Leu337.A, Cys341.A, Met344.A, Tyr348.A, Lys380.A, Leu383.A, Arg384.A, Val386.A, Gly387.A, Val390.A |
| F | -13.6 | Ile334.D, Leu337.D, Cys341.D, Met344.D, Tyr348.D, Lys380.D, Leu383.D, Arg384.D, Val386.D, Gly387.D, Val390.D | |
| G | -13.2 | Ile334.B, Leu337.B, Cys341.B, Met344.B, Tyr348.B, Lys380.B, Leu383.B, Arg384.B, Val386.B, Gly387.B, Val390.B | |
| H | -13.0 | Val336.B, Ile340.B, Met344.B, Val347.B, Tyr348.B, Trp461.B, Val464.B, Trp494.D, Val498.D, Leu501.D, Tyr525.D, Pro526.D, Leu529.D | |
| I | -13.0 | Trp494.A, Val498.A, Leu501.A, Tyr525.A, Pro526.A, Leu529.A, Val336.D, Ile340.D, Met344.D, Val347.D, Tyr348.D, Trp461.D, Val464.D | |
| J | -13.0 | Val336.A, Ile340.A, Met344.A, Val347.A, Tyr348.A, Trp461.A, Val464.A, Trp494.C, Val498.C, Leu501.C, Tyr525.C, Pro526.C, Leu529.C | |
| K | -12.9 | Phe552.A, Ser555.A, Ile556.A, Cys493.D, Trp494.D, Ala497.D, Pro526.D, Phe530.D | |
| L | -12.9 | Cys493.A, Trp494.A, Ala497.A, Pro526.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C | |
| M | -12.9 | Phe552.B, Ser555.B, Ile556.B, Cys493.C, Trp494.C, Ala497.C, Pro526.C, Phe530.C | |
| N | -13.6 | Ile334.C, Leu337.C, Cys341.C, Met344.C, Tyr348.C, Lys380.C, Leu383.C, Arg384.C, Val386.C, Gly387.C, Val390.C | |
| O | -13.0 | Trp494.B, Val498.B, Leu501.B, Tyr525.B, Pro526.B, Leu529.B, Val336.C, Ile340.C, Met344.C, Val347.C, Tyr348.C, Trp461.C, Val464.C | |
| P | -12.9 | Cys493.B, Trp494.B, Ala497.B, Pro526.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D | |
| 6d7p_IC | E | -15.4 | Phe328.B, Gly332.B, Ala333.B, Val336.B, Leu337.B, Ile340.B, Phe467.B, Ala468.B, Phe471.B, Trp494.D |
| F | -15.4 | Trp494.A, Phe328.D, Gly332.D, Ala333.D, Val336.D, Leu337.D, Ile340.D, Phe467.D, Ala468.D, Phe471.D | |
| G | -15.4 | Phe328.A, Gly332.A, Ala333.A, Val336.A, Leu337.A, Ile340.A, Phe467.A, Ala468.A, Phe471.A, Trp494.C | |
| H | -15.4 | Trp494.B, Phe328.C, Gly332.C, Ala333.C, Val336.C, Leu337.C, Ile340.C, Phe467.C, Ala468.C, Phe471.C | |
| TRPV6, plus 2-APB, Rat 6d7q | |||
| 6d7q_EC | E | -13.9 | Leu489.A, Cys493.A, Pro526.A, Met527.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C |
| F | -13.8 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Leu489.D, Cys493.D, Pro526.D, Met527.D, Phe530.D | |
| G | -13.8 | Phe552.B, Ser555.B, Ile556.B, Ala559.B, Ile563.B, Cys493.C, Pro526.C, Met527.C, Phe530.C | |
| H | -13.8 | Cys493.A, Met496.A, Ala497.A, Ile500.A, Pro526.A, Phe530.A, Phe533.A, Phe552.C, Ser555.C, Ile556.C | |
| I | -13.8 | Phe552.A, Ser555.A, Ile556.A, Cys493.D, Met496.D, Ala497.D, Ile500.D, Pro526.D, Phe530.D, Phe533.D | |
| J | -13.8 | Phe552.B, Ser555.B, Ile556.B, Cys493.C, Met496.C, Ala497.C, Ile500.C, Pro526.C, Phe530.C, Phe533.C | |
| K | -13.6 | Val336.B, Ile340.B, Trp461.B, Trp494.D, Ala497.D, Val498.D, Leu501.D, Pro526.D, Leu529.D | |
| L | -13.5 | Val336.A, Ile340.A, Trp461.A, Trp494.C, Ala497.C, Val498.C, Leu501.C, Pro526.C, Leu529.C | |
| M | -13.4 | Trp494.A, Val498.A, Leu501.A, Pro526.A, Leu529.A, Val336.D, Ile340.D, Trp461.D | |
| N | -13.8 | Cys493.B, Pro526.B, Met527.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D, Ala559.D, Ile563.D | |
| O | -13.8 | Cys493.B, Met496.B, Ala497.B, Ile500.B, Pro526.B, Phe530.B, Phe533.B, Phe552.D, Ser555.D, Ile556.D | |
| P | -13.3 | Trp494.B, Ala497.B, Val498.B, Leu501.B, Pro526.B, Leu529.B, Ile340.C, Trp461.C | |
| 6d7q_IC | E | -16.4 | Val336.B, Ile340.B, Val464.B, Phe467.B, Ala468.B, Phe471.B, Leu474.B, Trp494.D, Val498.D |
| F | -16.4 | Trp494.A, Val498.A, Phe328.D, Val336.D, Ile340.D, Val464.D, Phe467.D, Ala468.D, Phe471.D, Leu474.D | |
| G | -16.4 | Val336.A, Ile340.A, Val464.A, Phe467.A, Ala468.A, Phe471.A, Leu474.A, Trp494.C, Val498.C | |
| H | -16.4 | Trp494.B, Val498.B, Val336.C, Ile340.C, Val464.C, Phe467.C, Ala468.C, Phe471.C, Leu474.C | |
| TRPV6, Rat 6d7x | |||
| 6d7x_EC | E | -14.3 | Phe552.A, Ser555.A, Ile556.A, Cys493.D, Met496.D, Ala497.D, Pro526.D, Met527.D, Phe530.D |
| F | -14.3 | Cys493.A, Met496.A, Ala497.A, Pro526.A, Met527.A, Phe530.A, Phe552.C, Ser555.C, Ile556.C | |
| G | -14.3 | Phe552.B, Ser555.B, Ile556.B, Cys493.C, Met496.C, Ala497.C, Pro526.C, Met527.C, Phe530.C | |
| H | -13.3 | Ile334.A, Leu337.A, Cys341.A, Met344.A, Tyr348.A, Lys380.A, Leu383.A, Val390.A | |
| I | -13.2 | Tyr376.A, Leu389.A, Ile392.A, Val393.A, Val396.A, Leu400.A, Met439.A, Leu443.A | |
| J | -13.2 | Tyr376.D, Leu389.D, Ile392.D, Val393.D, Val396.D, Leu400.D, Met439.D, Leu443.D | |
| K | -13.3 | Ile334.B, Leu337.B, Cys341.B, Met344.B, Tyr348.B, Lys380.B, Leu383.B, Val390.B | |
| L | -12.8 | Trp494.A, Ala497.A, Val498.A, Leu501.A, Tyr525.A, Pro526.A, Leu529.A, Val336.D, Ile340.D, Trp461.D | |
| M | -12.7 | Val336.B, Ile340.B, Trp461.B, Trp494.D, Ala497.D, Val498.D, Leu501.D, Tyr525.D, Pro526.D, Leu529.D | |
| N | -12.5 | Ile334.D, Leu337.D, Tyr338.D, Ile340.D, Cys341.D, Met344.D, Lys380.D, Leu383.D, Val390.D | |
| O | -12.7 | Val336.A, Ile340.A, Trp461.A, Trp494.C, Ala497.C, Val498.C, Leu501.C, Tyr525.C, Pro526.C, Leu529.C | |
| P | -14.3 | Cys493.B, Met496.B, Ala497.B, Pro526.B, Met527.B, Phe530.B, Phe552.D, Ser555.D, Ile556.D | |
| Q | -13.2 | Tyr376.C, Leu389.C, Ile392.C, Val393.C, Val396.C, Leu400.C, Met439.C, Leu443.C | |
| R | -13.2 | Tyr376.B, Leu389.B, Ile392.B, Val393.B, Val396.B, Leu400.B, Met439.B, Leu443.B | |
| S | -12.7 | Trp494.B, Ala497.B, Val498.B, Leu501.B, Tyr525.B, Pro526.B, Leu529.B, Val336.C, Ile340.C, Trp461.C | |
| T | -12.5 | Ile334.C, Leu337.C, Tyr338.C, Ile340.C, Cys341.C, Met344.C, Lys380.C, Leu383.C, Val390.C | |
| 6d7x_IC | E | -14.6 | Ala333.B, Val336.B, Leu337.B, Ile340.B, Val464.B, Phe467.B, Ala468.B, Phe471.B, Trp494.D |
| F | -14.6 | Phe328.A, Ala333.A, Val336.A, Leu337.A, Val464.A, Phe467.A, Ala468.A, Phe471.A, Trp494.C | |
| G | -14.6 | Trp494.A, Phe328.D, Ala333.D, Val336.D, Leu337.D, Ile340.D, Val464.D, Phe467.D, Ala468.D, Phe471.D | |
| E | -14.6 | Trp494.B, Phe328.C, Ala333.C, Val336.C, Leu337.C, Val464.C, Phe467.C, Ala468.C, Phe471.C | |
| TRPV6, plus calmodulin, Human 6e2f | |||
| 6e2f_EC | E | -13.6 | Met345.B, Ile348.B, Tyr349.B, Ala498.C, Leu502.C, Tyr526.C, Pro527.C, Leu530.C |
| F | -13.6 | Cys494.A, Ala498.A, Pro527.A, Leu530.A, Phe531.A, Phe534.A, Phe553.B, Ser556.B, Ile557.B, Ala560.B, Ile564.B | |
| G | -13.5 | Cys494.C, Met497.C, Ala498.C, Ile501.C, Pro527.C, Leu530.C, Phe531.C, Phe534.C, Phe553.D, Ser556.D, Ile557.D | |
| H | -13.4 | Cys494.B, Met497.B, Ala498.B, Ile501.B, Pro527.B, Met528.B, Leu530.B, Phe531.B, Phe534.B, Ser556.C, Ile557.C, Ile564.C | |
| I | -13.4 | Met345.A, Ile348.A, Tyr349.A, Ala498.B, Leu502.B, Tyr526.B, Pro527.B, Leu530.B | |
| J | -13.4 | Ala498.A, Leu502.A, Tyr526.A, Pro527.A, Leu530.A, Met345.D, Ile348.D, Tyr349.D | |
| K | -13.6 | Ile341.C, Met345.C, Ile348.C, Tyr349.C, Ala498.D, Leu502.D, Tyr526.D, Pro527.D, Leu530.D | |
| L | -13.5 | Phe553.A, Ser556.A, Ile557.A, Ile564.A, Cys494.D, Met497.D, Ala498.D, Ile501.D, Pro527.D, Met528.D, Leu530.D, Phe531.D, Phe534.D | |
| 6e2f_IC | E | -15.9 | Leu337.A, Trp462.A, Val465.A, Phe468.A, Ala469.A, Gly471.A, Phe472.A, Trp495.B, Leu496.B, Ala498.B, Val499.B, Leu502.B, Leu530.B |
| F | -15.8 | Trp495.A, Leu496.A, Ala498.A, Val499.A, Leu502.A, Leu530.A, Leu337.D, Trp462.D, Val465.D, Phe468.D, Ala469.D, Gly471.D, Phe472.D | |
| G | -15.8 | Leu337.B, Trp462.B, Val465.B, Phe468.B, Ala469.B, Gly471.B, Phe472.B, Trp495.C, Leu496.C, Ala498.C, Val499.C, Leu502.C, Leu530.C | |
| H | -15.6 | Phe425.B, Phe456.B, Val459.B, Cys463.B, Met466.B, Thr479.B, Ile482.B, Gln483.B, Ile486.B, Phe504.C, Met554.C, Ile557.C, Thr558.C, Ala561.C, Ile565.C | |
| I | -15.6 | Phe425.A, Phe456.A, Met466.A, Thr479.A, Ile482.A, Gln483.A, Ile486.A, Phe504.B, Met554.B, Ile557.B, Thr558.B, Ala561.B, Ile565.B | |
| J | -16.4 | Phe425.C, Leu428.C, Phe456.C, Val459.C, Leu460.C, Cys463.C, Thr479.C, Ile482.C, Gln483.C, Ile486.C, Phe504.D, Met554.D, Ile557.D, Thr558.D, Ala561.D | |
| K | -16.4 | Leu337.C, Ile341.C, Trp462.C, Val465.C, Phe468.C, Ala469.C, Gly471.C, Phe472.C, Trp495.D, Leu496.D, Ala498.D, Val499.D, Leu502.D, Leu530.D | |
| L | -15.4 | Phe504.A, Met554.A, Ile557.A, Thr558.A, Ala561.A, Ile565.A, Phe425.D, Phe456.D, Cys463.D, Met466.D, Thr479.D, Ile482.D, Gln483.D, Ile486.D | |
| TRPV6, plus calmodulin, Rat 6e2g | |||
| 6e2g_EC | E | -15.1 | Ile340.A, Thr343.A, Met344.A, Val347.A, Tyr348.A, Trp461.A, Trp494.B, Ala497.B, Val498.B, Leu501.B, Tyr525.B, Leu529.B |
| F | -15.0 | Ile340.C, Thr343.C, Met344.C, Val347.C, Tyr348.C, Trp461.C, Ala497.D, Val498.D, Leu501.D, Tyr525.D, Leu529.D | |
| G | -14.8 | Ile340.B, Thr343.B, Met344.B, Val347.B, Tyr348.B, Trp461.B, Val464.B, Ala497.C, Val498.C, Leu501.C, Tyr525.C, Leu529.C | |
| H | -13.7 | Cys493.C, Ala497.C, Pro526.C, Leu529.C, Phe530.C, Phe552.D, Ser555.D, Ile556.D | |
| I | -13.6 | Cys493.B, Pro526.B, Phe530.B, Phe552.C, Ser555.C, Ile556.C, Ala559.C, Ile563.C | |
| J | -13.5 | Phe552.A, Ser555.A, Ile556.A, Ala559.A, Ile563.A, Cys493.D, Met496.D, Ala497.D, Pro526.D, Leu529.D, Phe530.D, Phe533.D | |
| K | -15.2 | Trp494.A, Ala497.A, Val498.A, Leu501.A, Tyr525.A, Leu529.A, Ile340.D, Met344.D, Val347.D, Tyr348.D, Trp461.D | |
| L | -13.5 | Cys493.A, Met496.A, Ala497.A, Pro526.A, Leu529.A, Phe530.A, Phe533.A, Phe552.B, Ser555.B, Ile556.B, Ala559.B, Ile563.B | |
| 6e2g_IC | E | -15.9 | Pro423.C, Phe424.C, Ile427.C, Phe455.C, Val458.C, Leu459.C, Cys462.C, Met465.C, Arg469.C, Thr478.C, Ile479.C, Ile481.C, Gln482.C, Ile485.C, Phe503.D, Ile556.D, Thr557.D, Ala560.D, Ile564.D |
| F | -15.4 | Pro423.B, Phe424.B, Ile427.B, Phe455.B, Val458.B, Leu459.B, Cys462.B, Met465.B, Thr478.B, Ile479.B, Ile481.B, Gln482.B, Ile485.B, Phe503.C, Ile556.C, Thr557.C, Ala560.C, Ile564.C | |
| G | -15.3 | Phe415.A, Gly416.A, Gln417.A, Pro423.A, Val426.A, Phe455.A, Val458.A, Leu459.A, Phe486.A, Ile556.B, Thr557.B, Ala560.B | |
| H | -14.9 | Phe503.A, Ile556.A, Thr557.A, Ala560.A, Phe415.D, Gly416.D, Gln417.D, Pro423.D, Val426.D, Phe455.D, Val458.D, Phe486.D | |
| I | -15.5 | Pro423.A, Phe424.A, Ile427.A, Phe455.A, Val458.A, Leu459.A, Cys462.A, Met465.A, Thr478.A, Ile481.A, Gln482.A, Ile485.A, Phe503.B, Ile556.B, Thr557.B, Ala560.B, Ile564.B | |
| J | -15.3 | Phe503.A, Ile556.A, Thr557.A, Ala560.A, Ile564.A, Phe424.D, Ile427.D, Phe455.D, Val458.D, Cys462.D, Met465.D, Thr478.D, Ile479.D, Ile481.D, Gln482.D, Ile485.D | |
| K | -13.0 | Phe414.B, Phe415.B, Gly416.B, Gln417.B, Pro423.B, Val426.B, Phe455.B, Ile556.C | |